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Magnesium and Cancer Research

Published on March 18, 2010


Magnesium repletion produced rapid disappearance of the periosteal tumors.[1]

Aleksandrowicz et al in Poland conclude that inadequacy of magnesium and antioxidants are important risk factors in predisposing to leukemias.[2] Other researchers found that 46% of the patients admitted to an ICU in a tertiary cancer center presented hypomagnesemia. They concluded that the incidence of hypomagnesemia in critically ill cancer patients is high.[3]In animal studies we find that magnesium deficiency has caused lymphopoietic neoplasms in young rats. A study of rats surviving magnesium deficiency sufficient to cause death in convulsions during early infancy in some, and cardiorenal lesions weeks later in others, disclosed that some of survivors had thymic nodules or lymphosarcoma.[4]

One would not normally think that Magnesium (Mg) deficiency can paradoxically increase the risk of, or protect against cancer yet we will find that just as severe dehydration or asphyxiation can cause death magnesium deficiency can directly lead to cancer. When you consider that over 300 enzymes and ion transport require magnesium and that its role in fatty acid and phospholipids acid metabolism affects permeability and stability of membranes, we can see that magnesium deficiency would lead to physiological decline in cells setting the stage for cancer. Anything that weakens cell physiology will lead to the infections that surround and penetrate tumor tissues. These infections are proving to be an integral part of cancer. Magnesium deficiency poses a direct threat to the health of our cells. Without sufficient amounts our cells calcify and rot. Breeding grounds for yeast and fungi colonies they become, invaders all too ready to strangle our life force and kill us.

Over 300 different enzymes systems rely upon magnesium to facilitate their catalytic action, including ATP metabolism, creatine-kinase activation, adenylate-cyclase, and sodium-potassium-ATPase.[5]

It is known that carcinogenesis induces magnesium distribution disturbances, which cause magnesium mobilization through blood cells and magnesium depletion in non-neoplastic tissues. Magnesium deficiency seems to be carcinogenic, and in case of solid tumors, a high level of supplemented magnesium inhibits carcinogenesis.[6] Both carcinogenesis and magnesium deficiency increase the plasma membrane permeability and fluidity. Scientists have in fact found out that there is much less Mg++ binding to membrane phospholipids of cancer cells, than to normal cell membranes.[7]

Magnesium protects cells from aluminum, mercury, lead, cadmium, beryllium and nickel.

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Magnesium in general is essential for the survival of our cells but takes on further importance in the age of toxicity where our bodies are being bombarded on a daily basis with heavy metals. Glutathione requires magnesium for its synthesis.[8] Glutathione synthetase requires ?-glutamyl cysteine, glycine, ATP, and magnesium ions to form glutathione.[9] In magnesium deficiency, the enzyme y-glutamyl transpeptidase is lowered.[10] According to Dr. Russell Blaylock, low magnesium is associated with dramatic increases in free radical generation as well as glutathione depletion and this is vital since glutathione is one of the few antioxidant molecules known to neutralize mercury.[11] Without the cleaning and chelating work of glutathione (magnesium) cells begin to decay as cellular filth and heavy metals accumulates; excellent environments to attract deadly infection/cancer.

There is drastic change in ionic flux from the outer and inner cell membranes both in the impaired membranes of cancer, and in Mg deficiency.

Anghileri et al[12],[13] proposed that modifications of cell membranes are principal triggering factors in cell transformation leading to cancer. Using cells from induced cancers, they found that there is much less magnesium binding to membrane phospholipids of cancer cells, than to normal cell membranes.[14] It has been suggested that Mg deficiency may trigger carcinogenesis by increasing membrane permeability.[15] Magnesium deficient cells membranes seem to have a smoother surface than normal, and decreased membrane viscosity, analogous to changes in human leukemia cells.[16],[17] There is drastic change in ionic flux from the outer and inner cell membranes (higher Ca and Na; lower Mg and K levels), both in the impaired membranes of cancer, and of Mg deficiency. And we find that lead (Pb) salts, are more leukemogenic when given to Mg deficient rats, than when they are given to Mg-adequate rats, suggesting that Mg is protective.[18]

Magnesium has an effect on a variety of cell membranes through a process involving calcium channels and ion transport mechanisms. Magnesium is responsible for the maintenance of the trans-membrane gradients of sodium and potassium.

Long ago researchers postulated that magnesium supplementation of those who are Mg deficient, like chronic alcoholics, might decrease emergence of malignancies[19] and now modern researchers have found that all types of alcohol — wine, beer or liquor — add equally to the risk of developing breast cancer in women. The researchers, led by Dr. Arthur Klatsky of the Kaiser Permanente Medical Care Program in Oakland, Calif., revealed their findings at a meeting of the European Cancer Organization in Barcelona in late 2007. It was found that women who had one or two drinks a day increased their risk of developing breast cancer by 10 percent. Women who had more than three drinks a day raised their risk by 30 percent. The more one drinks the more one drives down magnesium levels.

Breast cancer is the second most common cancer killer of women, after lung cancer. It will be diagnosed in 1.2 million people globally this year and will kill 500,000.

According to data published in the British Journal of Cancer in 2002, 4 percent of all breast cancers — about 44,000 cases a year — in the United Kingdom are due to alcohol consumption. It’s an important question though, and one not asked by medical or health officials, is it the alcohol itself or the resultant drop in magnesium levels that is cancer provoking? Though some studies have shown that light- to moderate alcohol use can protect against heart attacks it does us no good to drink if it causes cancer. Perhaps if magnesium was supplemented in women drinkers who were studied there would have been no increase of cancer from drinking.

Alcohol has always been known to deplete magnesium, and is one of the first supplements given to alcoholics when they stop and attempt to detoxify and withdraw.

Researchers from the School of Public Health at the University of Minnesota have just concluded that diets rich in magnesium reduced the occurrence of colon cancer.[20] A previous study from Sweden[21] reported that women with the highest magnesium intake had a 40 per cent lower risk of developing the cancer than those with the lowest intake of the mineral.

Magnesium stabilizes ATP[22], allowing DNA and RNA transcriptions and repairs.[23]

The anti-colon cancer effects of calcium are linked to magnesium levels, says a new study. Researchers from Vanderbilt University found that low ratios of the minerals were associated with reduced risk of colorectal cancer, according to findings presented at the Seventh Annual American Association for Cancer Research International Conference on Frontiers in Cancer Prevention Research. Both high magnesium and calcium levels have been linked to reduced risks of colon cancer but studies have also shown that high calcium levels inhibit the absorption of magnesium. According to Qi Dai, MD, PhD, and co-workers, Americans have high calcium intake, but also a high incidence of colorectal cancer. “If calcium levels were involved alone, you’d expect the opposite direction. There may be something about these two factors combined – the ratio of one to the other – that might be at play,” said Dai. The risk of colorectal cancer adenoma recurrence was reduced by 32 per cent among those with baseline calcium to magnesium ratio below the median in comparison to no reduction for those above the median,” said Dai.[24]

Pre-treatment hypomagnesemia has been reported in young leukemic children, 78% of whom have histories of anorexia, and have excessive gut and urinary losses of Mg.[25]

Several studies have shown an increased cancer rate in regions with low magnesium levels in soil and drinking water, and the same for selenium. In Egypt the cancer rate was only about 10% of that in Europe and America. In the rural fellah it was practically non-existent. The main difference was an extremely high magnesium intake of 2.5 to 3g in these cancer-free populations, ten times more than in most western countries.[26]

The School of Public Health at the Kaohsiung Medical College in, Taiwan, found that magnesium also exerts a protective effect against gastric cancer, but only for the group with the highest levels.[27]

If we looked it would probably be very difficult to find a cancer patient with anywhere near normal levels of cellular magnesium meaning cancer probably does not exist in a physical cellular environment full of magnesium. It makes perfect medical sense to saturate the body with magnesium through transdermal means. Magnesium deficiency has been implicated in a host of clinical disorders but the medical establishment just cannot get it through its thick skull that it is an important medicine.

It is as if the collective medical profession had just pulled the plug on medical intelligence. In fact it has done exactly this and it seems too late for it to redefine itself, which is a tragedy. Though magnesium improves the internal production of defensive substances, such as antibodies and considerably improves the operational activity of white granulozytic blood cells (shown by Delbert with magnesium chloride), and contributes to many other functions that insure the integrity of cellular metabolism, no one thinks to use it in cancer as a primary treatment. It is even worse than this, the medical establishment does not even use magnesium as a secondary treatment or even use it at all and gladly uses radiation and chemo therapy, both of which force magnesium levels down further.

To not replete cellular magnesium levels would be negligent especially in the case of cancer where a person’s life is on the line. An oncologist who ignores his patient’s magnesium levels would be analogous to an emergency room physician not rushing resuscitation when a person stops breathing. If one elects to have or has already had chemotherapy they have four times the reason to pay attention to a concentrated protocol aimed at replenishing full magnesium cellular stores.

Magnesium chloride is the first and most important item in any person’s cancer treatment strategy. Put in the clearest terms possible, our suggestion from the first day on the Survival Medicine Cancer Protocol is to almost drown oneself in transdermally applied magnesium chloride. It should be the first not the last thing we think of when it comes to cancer. It takes about three to four months to drive up cellular magnesium levels to where they should be when treated intensely transdermally but within days patients will commonly experience its life saving medical/healing effects. For many people whose bodies are starving for magnesium the experience is not too much different than for a person coming out of a desert desperate for water. It is that basic to life, that important, that necessary.

That same power found in magnesium that will save your life in the emergency room during cardiac arrest, that will diminish damage of a stroke if administered in a timely fashion is the same power that can save one’s life if one has cancer. All a patient has to do is pour it into their baths or spray it right onto their bodies. What could be simpler?

Magnesium chloride, when applied directly to the skin, is transdermally absorbed and has an almost immediate effect on chronic and acute pain.

Special Note on Calcium and Cancer:

Experts say excessive calcium intake may be unwise in light of recent studies showing that high amounts of the mineral may increase risk of prostate cancer. “There is reasonable evidence to suggest that calcium may play an important role in the development of prostate cancer,” says Dr. Carmen Rodriguez, senior epidemiologist in the epidemiology and surveillance research department of the American Cancer Society (ACS). Rodriguez says that a 1998 Harvard School of Public Health study of 47,781 men found those consuming between 1,500 and 1,999 mg of calcium per day had about double the risk of being diagnosed with metastatic (cancer that has spread to other parts of the body) prostate cancer as those getting 500 mg per day or less. And those taking in 2,000 mg or more had over four times the risk of developing metastatic prostate cancer as those taking in less than 500 mg.

Calcium and magnesium are opposites in their effects on our body structure. As a general rule, the more rigid and inflexible our body structure is, the less calcium and the more magnesium we need.

Later in 1998, Harvard researchers published a study of dairy product intake among 526 men diagnosed with prostate cancer and 536 similar men not diagnosed with the disease. That study found a 50% increase in prostate cancer risk and a near doubling of risk of metastatic prostate cancer among men consuming high amounts of dairy products, likely due, say the researchers, to the high total amount of calcium in such a diet. The most recent Harvard study on the topic, published in October 2001, looked at dairy product intake among 20,885 men and found men consuming the most dairy products had about 32% higher risk of developing prostate cancer than those consuming the least.

The adverse effects of excessive calcium intake may include high blood calcium levels, kidney stone formation and kidney complications.[28] Elevated calcium levels are also associated with arthritic/joint and vascular degeneration, calcification of soft tissue, hypertension and stroke, and increase in VLDL triglycerides, gastrointestinal disturbances, mood and depressive disorders, chronic fatigue, and general mineral imbalances including magnesium, zinc, iron and phosphorus.  High calcium levels interfere with Vitamin D and subsequently inhibit the vitamin’s cancer protective effect unless extra amounts of Vitamin D are supplemented.[29]

Magnesium is the mineral of rejuvenation and prevents the calcification of our organs and tissues that is characteristic of the old-age related degeneration of our body.

Recommendations of magnesium to calcium ratios range from 1:2 to 1:1. For those interested in preventing cancer one should look closely at the 1:1 camp and during the first six months of treatment one should be looking at ten parts magnesium to one part calcium. In reality one need not even count the ratio during the first months for the only real danger of extremely high magnesium levels comes with patients suffering from kidney failure. If one is at all concerned about their calcium intake one should eat foods high in both calcium and magnesium like toasted sesame seeds.

Up to 30% of the energy of cells is used to pump calcium out of the cells.

Doctors who have used intravenous magnesium treatments know the benefits of peaking magnesium levels, even if only temporarily. For the cancer patient the transdermal approach combined with oral use offers the opportunity to take magnesium levels up strongly and quickly. For emergency situations three applications a day, for urgent two treatments would be indicated though one strong treatment with an ounce of a natural magnesium chloride solution spread all over the body like a sun screen is a powerful systemic treatment.

It is medical wisdom that tells us that magnesium is actually the key to the body’s proper assimilation and use of calcium, as well as other important nutrients. If we consume too much calcium, without sufficient magnesium, the excess calcium is not utilized correctly and may actually become toxic, causing painful conditions in the body. Hypocalcemia is a prominent manifestation of magnesium deficiency in humans (Rude et al., 1976). Even mild degrees of magnesium depletion significantly decreases the serum calcium concentration (Fatemi et al., 1991).

Calcium requirement for men and women is lower than previously estimated.[30]

[1] Hunt, B.J., Belanger, L.F. Localized, multiform, sub-periosteal hyperplasia and generalized osteomyelosclerosis in magnesium-deficient rats. Calcif. Tiss. Res. 1972; 9:17-27.

[2]Aleksandrowicz, J., Blicharski, J., Dzigowska, A., Lisiewicz, J. Leuko- and oncogenesis in the light of studies on metabolism of magnesium and its turnover in biocenosis. Acta Med. Pol. 1970; 11:289-302. (abstr: Blood 1971; 37:245)

[3] D. Deheinzelin, E.M. Negri1, M.R. Tucci, M.Z. Salem1, V.M. da Cruz1, R.M. Oliveira, I.N. Nishimoto and C. Hoelz. Hypomagnesemia in critically ill cancer patients: a prospective study of predictive factors. Braz J Med Biol Res, December 2000, Volume 33(12) 1443-1448

[4] Bois, P. Tumour of the thymus in magnesium-deficient rat. Nature 1964; 204:1316.

[5] Magnesium is used in the creatine-phosphate formation, activates the alkaline phosphatase and pyrophosphatase, stabilizes nucleic acid synthesis, concerning DNA synthesis and degradation, as well as the physical integrity of the DNA helix, activates amino acid and protein synthesis, and regulates numerous hormones.

[6] Durlach J, Bara M, Guiet-Bara A, Collery P. Relationship between magnesium, cancer and carcinogenic or anticancer metals. Anticancer Res. 1986 Nov-Dec;6(6):1353-61.

[7]Anghileri, L.J. Magnesium concentration variations during carcinogenesis. Magnesium Bull. 1979; 1:46-48.

[9] Virginia Minnich, M. B. Smith, M. J. Brauner, and Philip W. Majerus. Glutathione biosynthesis in human erythrocytes. Department of Internal Medicine, Washington University School of Medicine, J Clin Invest. 1971 March; 50(3): 507–513. Abstract: The two enzymes required for de novo glutathione synthesis, glutamyl cysteine synthetase and glutathione synthetase, have been demonstrated in hemolysates of human erythrocytes. Glutamyl cysteine synthetase requires glutamic acid, cysteine, adenosine triphosphate (ATP), and magnesium ions to form ?-glutamyl cysteine. The activity of this enzyme in hemolysates from 25 normal subjects was 0.43±0.04 ?mole glutamyl cysteine formed per g hemoglobin per min. Glutathione synthetase requires ?-glutamyl cysteine, glycine, ATP, and magnesium ions to form glutathione. The activity of this enzyme in hemolysates from 25 normal subjects was 0.19±0.03 ?mole glutathione formed per g hemoglobin per min. Glutathione synthetase also catalyzes an exchange reaction between glycine and glutathione, but this reaction is not significant under the conditions used for assay of hemolysates. The capacity for erythrocytes to synthesize glutathione exceeds the rate of glutathione turnover by 150-fold, indicating that there is considerable reserve capacity for glutathione synthesis. A patient with erythrocyte glutathione synthetase deficiency has been described. The inability of patients’ extracts to synthesize glutathione is corrected by the addition of pure glutathione synthetase, indicating that there is no inhibitor in the patients’ erythrocytes.

[10] Braverman, E.R. (with Pfeiffer, C.C.)(1987). The healing nutrients within: Facts, findings and new research on amino acids. New Canaan: Keats Publishing

[12] Anghileri, L.J. Magnesium concentration variations during carcinogenesis. Magnesium Bull. 1979; 1:46-48.

[13] Anghileri, L.J., Collery, P., Coudoux, P., Durlach, J. (Experimental relationships between magnesium and cancer.) Magnesium Bull. 1981; 3:1-5

[14] Anghileri, L.J., Heidbreder, M., Weiler, G., Dermietzel, R. Hepatocarcinogenesis by thioacetamide: correlations of histological and biochemical changes, and possible role of cell injury. Exp. Cell. Biol. 1977; 45:34-47.

[15] Blondell, J.W. The anticancer effect of magnesium. Medical Hypothesis 1980; 6:863-871.

[16] Whitney, R.B., Sutherland, R.M. The influence of calcium, magnesium and cyclic adenosine 3’5?-monophosphate on the mixed lymphocyte reaction. J. Immunol. 1972; 108:1179-1183.

[17] Petitou, M., Tuy, F., Rosenfeld, C., Mishal, Z., Paintrand, M., Jasmin, C., Mathe, G., Inbar, M. Decreased microviscosity of membrane lipids in leukemic cells; two possible mechanisms. Proc. Natl. Acad. Sci. USA 1978; 75:2306-2310.

[18] Hass, G.M., McCreary, P.A., Laing, G.H., Galt, R.M. Lymphoproliferative and immumunologic aspects of magnesium deficiency. In Magnesium in Health and Disease (from 2nd Intl Mg Sympos, Montreal, Canada, 1976), b Eds. M. Cantin, M.S. Seelig, Publ. Spectrum Press, NY, 1980, pp 185-200

[19] Collery, P., Anghileri, L.J., Coudoux, P., Durlach, J. (Magnesium and cancer: Clinical data.) Magnesium Bull. 1981; 3:11-20.

[20] American Journal of Epidemiology (Vol. 163, pp. 232-235)

[21] Journal of the American Medical Association, Vol. 293, pp. 86-89

[22] Mg2+ is critical for all of the energetics of the cells because it is absolutely required that Mg2+ be bound (chelated) by ATP (adenosine triphosphate), the central high energy compound of the body.  ATP without Mg2+ bound cannot create the energy normally used by specific enzymes of the body to make protein, DNA, RNA, transport sodium or potassium or calcium in and out of cells, nor to phosphorylate proteins in response to hormone signals, etc.  In fact, ATP without enough Mg2+ is non-functional and leads to cell death.  Bound Mg2+ holds the triphosphate in the correct stereochemical position so that it can interact with ATP using enzymes and the Mg2+ also polarizes the phosphate backbone so that the ‘backside of the phosphorous’ is more positive and susceptible to attack by nucleophilic agents such as hydroxide ion or other negatively charged compounds. Bottom line, Mg2+ at critical concentrations is essential to life,” says Dr. Boyd Haley who asserts strongly that, “All detoxification mechanisms have as the bases of the energy required to remove a toxicant the need for Mg-ATP to drive the process.  There is nothing done in the body that does not use energy and without Mg2+ this energy can neither be made nor used.” Detoxification of carcinogenic chemical poisons is essential for people want to avoid the ravages of cancer. The importance of magnesium in cancer prevention should not be underestimated.

[23] Magnesium has a central regulatory role in the cell cycle including that of affecting transphorylation and DNA synthesis, has been proposed as the controller of cell growth, rather than calcium. It is postulated that Mg++ controls the timing of spindle and chromosome cycles by changes in intracellular concentration during the cell cycle. Magnesium levels fall as cells enlarge until they reach a level that allows for spindle formation. Mg influx then causes spindle breakdown and cell division.


[25] Paunier, L., Radde, I.C.: Normal and abnormal magnesium metabolism. Bull. of Hosp. for Sick Childr. (Toronto) 1965; 14:16-23.

[26] MAY 19, 1931, Dr. P. Schrumpf-Pierron presented a paper entitled “On the Cause Of the Rarity of Cancer in Egypt,” which was printed in the Bulletin of the Academy of Medicine, and the Bulletin of the French Association for the Study of Cancer in July, 1931.

[27] Yang CY et al. Jpn J Cancer Res.1998 Feb;89 (2):124-30. Calcium, magnesium, and nitrate in drinking water and gastric cancer mortality.

[29] Accu-Cell Nutrition; Calcium and Magnesium

[30] Am J Clin Nutr. 2007 Oct;86(4):1054-1063. Calcium requirements: new estimations for men and women by cross-sectional statistical analyses of calcium balance data from metabolic studies.Hunt CD, Johnson LK. US Department of Agriculture, Agricultural Research Service, Grand Forks Human Nutrition Research Center, Grand Forks, ND.

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For questions pertaining to your own personal health issues or for specific dosing of Dr. Sircus's protocol items please seek a consultation or visit our knowledge base to see if your question may have been answered previously.
  • moritz saabel

    Interestingly I have just read a study showing a positive relationship between calcium intake and all cardiovasscular disease cancer and all cause mortality!

  • has20birds

    I had two 5 cm lumps in my breast and lymph node. I was diagnosed with IDC at stage 3. I put three handfuls of magnesium sulfate in my bath several times a week, took L-glutamine, CoQ10, IP6 (rice bran), resveratrol, vitamin D, baby aspirin (kills yeast), and did no dairy while I underwent chemo. I did an anti-fungus diet. I also avoided vitamin C like the plague since it makes your body dump iron and cancer scavenges iron to create its own oxygen supply. Six months later the surgeon removed an “unviable” tumor and all the lymph nodes under my arm. One had cancer. Sounds like you’re right on track to me finding the correlation between iodine, magnesium, and vitamin D. Thanks for this!

  • Ken Baldrey

    I have been soaking in Dead Sea salts with sodium bicarbonate for several years now with I think excellent results. Also I am alternating soaking with Epsom salts with sodium bicarbonate. This also seems to work well and produces the characteristic bubbles and effervescent mist when used with water jets that Dr. Sircus describes for magnesium chloride and sodium bicarbonate. I use up to 7 lbs. each SBC and Epsom salts or Dead Sea salts about once every two weeks for 60 to 90 minutes luke warm. It is a wonderful tonic for the whole body.
    I wonder if anyone else uses a similar protocol for soaking or if anyone reports on the Epsom salt/SBC combination, it’s a lot more available and cheaper in bulk than magnesium chloride? Also not as harsh. I agree with Dr. Sircus that higher concentrations closer to saturation are better.

    • Claudia French – IMVA Staff


      What you are describing will work just fine for a nice relaxing bath but our research has shown that the magneisum absorbed from epsom salts (magnesium sulfate) is not absorbed as efficiently as magnesium chloride and the benefits of magnesium from epsom salts don’t last near as long as they do when magnesium chloride is used. This was shown by the prominent researcher in magnesium, named Jean Durlach and is referenced in the Transdermal Magnesium Therapy book.

      Personally I use magnesium chloride bath flakes from LL’s Magnetic Clay in baths with baking soda and without baking soda, a few times per week and I don’t find it the least bit “harsh” as you are stating.

  • Paul Blessington

    Please ignore first message as the first half was lost. can you explain the difference between mag chloride and mag sulphate. I have got epsom salts to add to my bath – but is that as effective as chloride? I have a stage 4 cancer of unknown origin, but thought to be from my GI tract.
    Thanks for your help.
    Canberra ACT

  • Judy

    Good day
    My friends husband has been diagnosed with stage 4 colon cancer – the tumour is over 15cm long and the cancer is in his whole abdominal cavity and going to his legs.
    I have bought magnesium oil for them – will this help? What else should he do? He is on a limited diet due to the bag that was put in on Monday (the doctor didn’t remove any of the colon as at this point he is an inoperable state)
    Thank you
    Judy x

  • Erick Mulero

    Im using magnesium cloride, because i have high blood pressure..since im takin magnesiwm cloride i feel much better and liquid retention disapeared..My son was very ilkl with imsomnia and he is cured , since the intake of magnesium cloride..Im using the tablets of 500 mg..thanks a lot for this site..

  • Ron


    My mother has recently (in the last week) discovered a lump in her breast and has received confirmation of a 7mm tumor through a sonogram and mammogram. She had her biopsy consult yesterday and the physician expressed concern that there could be another smaller lump in the other breast and immediately began discussing mastectomies.

    Over the last couple of days, I have researched alternative therapies and through multiple links found your informative site. Your site and Dr. Sircus mentions a multiple approach attack on cancer; not exclusively mag therapy or Sod Bic therapy. My question is; where can I find your resources (either in www or book resources) describing a multiple approach attack, if it exists.

    I would hope that nutritional recommendations would be available as well. Your advice is very appreciated. Thank you in advance.


    • Claudia French – IMVA Staff

      Dear Ron,

      Right now there is a great deal of information on our Cancer site:

      You can get a good idea from this about Dr. Sircus’s multiple approach to cancer treatment. Please also see our book
      for even more information. You can view the Table of Contents here:

      Later this year (probably toward the end of the year) IMVA will be publishing a new cancer book on Breast and Prostate Cancer. We will make an announcement when that gets closer to publication.

      You can also request a private consultation with Dr. Sircus for a brief consultation or to develope a specific plan for your mother’s treatment, if the book does not answer all your questions.

  • C. Rios

    Good morning,
    please tell me if you have any experience with Magnesium and Sodium Bicarbonate in the treatment of Leukemia ( CLL ).

    • Claudia French – IMVA Staff

      to C. Rios,

      You would have to speak directly with Dr. Sircus about his personal case studies.

      We know that magnesium is often deficient in leukemia and that since leukemia is considered a fungus, sodium bicarbonate can be effective against it.

  • Steve

    Dear Claudia;

    My wife has been suffering from back/rib pain for 4 months – we just found out its Grade 1 Chondrosarcoma cancer in T7
    The doc tells us this T7 must be removed but its a very difficult area to get into for removal of the tumor.

    I am asking if Magnesium would work for this type of cancer?
    If so – how is the best way to get Magnesium into this affected area? What would be the oral does per day?
    Should she do foot baths to absorb more Magnesium into the body to fight the cancer?
    What other methods are recommended for her situation?

    • Claudia French – IMVA Staff

      Dear Steve,
      Sorry to hear about your wife’s problem.

      She could try the magnesium in combination with sodium bicarbonate and possibly some other things on Dr. Sircus’ protocol. Magnesium is necessary as a supportive supplement in most cancers. Sodium bicarbonate is effective in cancer treatment too. Go to our site on sodium bicarbonate and read about this. pH must be checked daily when using it orally and pH allowed to get to 8 for a few days to neutralize the cancer.

      Magnesium can be applied topically right over the site of the tumor, and a foot bath will be helpful as well. But specific dosages cannot be given to you here, without more information and Dr. Sircus would require a personal consultation to give you more specifics.

  • Rick

    Dear Claudia,

    Thanks a million for your reply. Question, can I take magnesuim in pill form as I know that it offered in health food stores. If so, what amount should be taken daily? Is it necessary to apply on the skin and to do the footbaths if there is NO cancer present?

    • Claudia French – IMVA Staff


      You can take magnesium in pill form but it might take up to a year to replenish your magnesium levels. Only about 30-40% of the magnesium from tablets is actually absorbed from any oral maganesium product due to causing diarrhea, to intestinal problems that prevent absorption etc. The RDA (recommended daily allowance) for a man over age 30 is 420 mg./day as recommended by the National Institutes of Health:

      However many researchers and doctors believe that this is way too low and that we need double this amount if not more. However when taking double in oral forms it frequently causes diarrhea, and this is the single most limiting factor to getting enough magnesium into our bodies.

      Even though you have to order it over the Internet, it is worth it to get the magnesium oil. This is why we don’t recommend any specific oral form…..none are really good, especially not magnesium oxides, which are the most difficult to absorb.

      Doing the footbaths with magnesium oil and spraying on the skin is only necessary if you want to raise your magneisum levels. oral pills will take forever to get levels up and when you consider that almost everyone is magnesium deficient …well then they should use magnesium transdermally. Magnesium deficiencies cause a whole lot of problems besides just cancer as you will see as you read up on magnesium on our magnesium site:

  • Rick

    Two years ago, I was diagnosed with stage 1 prostate cancer. I wa 64 years old at the time. After evaluating my options,I decided to have the prostate removed as the tumors were inside the prostate with little danger of growing outside the prostate at the time. So far, my PSA has been less than 1. Please tell me the amount of magnesium that I should be taking at this time. I am concerned that a magnesuim maintenance system should be implemented. VERY CONCERNED

    Thank you so very much

    • Claudia French – IMVA Staff


      For cancer prevention you need to keep your stores of magnesium up to par at all times. The fastest way to do this is to use Ancient Minerals Magnesium OIl at the rate of 1=2oz per day on your body as a spray or massage oil. Dr. Norman Shealy, developer of the TENS unit for pain, and considered Father of Holistic Medicine, did experiments showing this.

      Dr. Shealy showed that through daily spraying and foot soaks magnesium levels rose more rapidly than any oral magnesium product:

      Our purpose was to research whether or not magnesium was absorbed through the skin. Exclusion factors included anyone taking oral or IV magnesium during the last 6 weeks and smokers. Individuals sprayed a solution of 50% Magnesium Oil over the entire body once daily for a month and did a 20 minute foot soak in Magnesium Oil once daily for a month. Subjects had a baseline Intracellular Magnesium Test documenting their deficiency and another post-Intracellular Magnesium Test after 1 month of daily soaks.

      The results were impressive. Twelve of sixteen patients, 75%, had significant improvements in intracellular magnesium levels after only four weeks of foot soaking and skin spraying.

      Typical Results

      Test results before and after 4 weeks of foot soaks:

      Foot Soaking

      Reference Range


      33.9 – 41.9

      3.2 – 5.0

      80.0 – 240.0

      3.8 – 5.8

      3.4 – 6.0

      14.2 – 17.0

      3.5 – 4.3

      7.8 – 10.9

      1.8 – 3.0

      25.8 – 52.4

      2.4 – 4.6

      21.5 – 44.6

      This is the first known proof of absorption of magnesium through the skin! And it suggests that 70% of individuals reported to have improved with use of this unique oil improved because of increased intracellular magnesium. From a safety point of view, there is no other approach that offers so much to so many.

  • Catharine

    My husband was diagnosed with prostate cancer. We have worked with supplements, diet and exercise, but have not beat it yet. What would you do in the same situation? I have been looking at Dr. Simoncini’s sodium bicarb protocol, but can’t find anyone to follow it. We just lost the doctor we were working with and now the doctors left just tell him to have surgery. Your help is greatly appreciated!

    • claudia


      Dear Catherine,
      One thing you should do is read Dr. Sircus’ book on Sodium Bicarbonate… it you will find that there are many things you can do to overcome prostate cancer without a doctor’s assistance and one of them is using sodium bicarbonate orally. This and other books are available on the IMVA Publications site.

      Claudia French

  • Gretchen

    I have just discovered your website from the reference in Dr. Carolyn Dean’s blogs on magnesium. I have a couple questions as I am new to this whole magnesium thing. I have been experiencing constant eyelid twitching for the past 6 months. Just over the past month I have noticed other mild twiching in other parts of my body (feet, calves, etc..) In Dr. Dean’s book she says that twitching is a result of an overactive nervous system, and that it can be helped by mag supplementation. I have just started to supplement w/Angstrom magnesim per her recommendation along with powdered Mag Citrate. I am just not sure how many mg/day I should be taking and am wondering if I should use the foot baths as well. I am so anxious for this annoying problem to be gone! Do you have any idea how long it might take to improve? Thank you for any help you might be able to provide!

    • claudia

      At the IMVA, we believe that transcdermal application of magnesium oil will get levels up faster than oral preparations. You would have to read Dr. Sircus’ books to fully understand why. But if your problem is related to a magnesium deficiency, you should notice an almost immediate improvement with magnesium oil use. Try it and see.

      Claudia French

  • Sal

    When you say that a Cancer patient should almost ‘drown oneself” in transdermally applied Magnesium choloride, how much are you talking about? Besides spraying yourself with Magnesium Oil every morning, how much should be put in a bath?

    • claudia


      Because you want to keep magnesium levels at the maximum in cancer treatment, you should consider using at least 2 oz on your skin per day and a pound or more in baths to start out with till your levels are raised. Foot baths are effective too and it ususally takes about a month or two to increase levels in your body. This is of course dependent on healthy kidneys which will remove any magnesium excess from the body.

      Magnesium protects against many cancer causing agents and is often depleted during chmotherapy.

      Claudia French RN, LPHA

  • rachel

    Thank you very much for the wonderful important knowledge.
    I have the magnesium chloride food grade powder or to be more accurate, granules. I put it in a sprayer resolved in water and spray every two days. I’m not sure as to the ratio between water and Magnesium. Can you help with that?
    Thanks, Rachel

  • sandra

    I have read so many of your articles about magnesium. What are the recommended daily doses for women over 50 and men. Also, what is the best form of magnesium to take. I know transdermally but it is not available where I live. Also what is the ratio between calcium nowadays. I have never seen magnesium with gluthione. And even if one takes it transdermally where do they get the gluthione from.

    • magnesiumforlife

      Adequate magensium allows for glutathione to be produced in our bodies. However, glutathione can be taken in tablet form and sources are shown on our product sources site at:

      Also, International sources for manesium oil and flakes are listed there as well.

      The RDA of magnesium reflects the bare minimum and the calcium to magnesium ratio should be at least 1:1. We have overburdened ourselves with calcium.

      Best Wishes,
      Claudia French RN, LPHA
      Assistant Director, IMVA

  • Chris Masters

    We know that dairy products interfere in health mainly because of pasteurization.
    The raw milk has all the goodness of whole food.
    I has enzymes intact,also contains range of unadulterated minerals and proteins.
    The calcium from raw milk gets transported to the bones, instead into the bloodstream.
    I think there is a great deal of confusion out there when word “dairy products” is used, since the raw milk has been outlawed in developed countries.
    Brings to mind the orthodox medicine reps. peddling drugs disregarding long years of medical knowledge.
    I congratulate you for producing wonderful, informative website.
    Yours in health
    Chris Masters
    Thebarton South Australia