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Pharmaceuticals Drive Magnesium Levels Lower

Published on June 29, 2012


Because magnesium deficiency causes all kinds of havoc with our cell physiology and worsens as we age, appropriate magnesium supplementation will not only help ensure we don’t age so fast but it also will prevent many of the major diseases we are facing today. Research published in the American Journal of Epidemiology in 2002 showed that when the diets of 2,566 children ages 11-19 were studied, less than 14% of boys and 12% of girls had adequate intakes of magnesium.

When magnesium is deficient, things begin to die, but when our body’s magnesium levels are topped off, our body physiology tends to hum along like a racecar yielding higher performance along many physiological parameters. Most doctors do not want to acknowledge that magnesium deficiency can lead directly to cancer, thus to a significantly shorter life. Same goes for diabetes and heart disease—magnesium deficiency brings on these diseases.

Magnesium is a vital mineral whose lack leaves us open to not only damage from radiation but also damage from heavy metals and the thousands of chemicals to which we are commonly exposed. Without sufficient magnesium, the body accumulates toxins and acid residues, degenerates rapidly, and ages prematurely.

Magnesium is the “lamp of life”—it operates at the core of physiology offering us what can only be called scientific miracles in medicine. All of life collapses around its loss. The realization that magnesium is at the center of life in chlorophyll should help us place magnesium in the temple where it deserves to be.

The most perfect medicine in the world is the one you have to have—no matter what—to continue your life. There are certain substances, all nutritional in nature, that provide essential lifelines to happy and fully functional cells. Though contemporary medicine does not want to admit the truth and reality about diseases and their causes, it is clear that nutritional law holds the key to the resolution of disease—not pharmaceuticals that are toxic and damaging to cellular environments.

Anything that drives down magnesium levels is going to hurt us. Many pharmaceutical drugs drive magnesium levels into dangerous zones and surgery done without increasing magnesium levels is more dangerous than surgery done when magnesium is administered before, during and after surgery. Dr. Matthias Rath says, “Almost all the prescription drugs currently taken by millions of people lead to a gradual depletion of vitamins and other essential cellular nutrients in the body.”

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Nutrients Depleted


Vitamins A, B-12, C, E, K, Biotin, Calcium, Iron, Magnesium, Potassium


Copper, Iron, Magnesium, Zinc


Vitamins B-2, B-12, C, F, K, Folic Acid, Calcium, Magnesium

Antidiabetics (Oral)

Vitamins B-2, B-12, C, D, Folic Acid


Vitamin C


Calcium, Folic Acid, Iron, Potassium, Vitamins C, B Complex

Other drugs or substances that cause loss of body magnesium:

  • Cocaine
  • Beta-adrenergic agonists (for asthma)
  • Corticosteroids (CS) (for asthma)
  • Theophylline (for asthma)
  • Diuretics
  • Thiazide
  • Phosphates (found in cola drinks)
  • Nicotine
  • Insulin
  • Alcohol

Proton Pump Inhibitors

The U.S. Food and Drug Administration (FDA) is informing the public that prescription proton pump inhibitor (PPI) drugs may cause low serum magnesium levels (hypomagnesemia) if taken for prolonged periods of time (in most cases, longer than one year). Information about the potential risk of low serum magnesium levels from PPIs will be added to the WARNINGS AND PRECAUTIONS sections of the labels.

In 2009, approximately 21 million patients filled prescriptions for proton pump inhibitor (PPI) drugs that drive magnesium serum levels down. In approximately one-quarter of the cases reviewed, magnesium supplementation alone did not improve low serum magnesium levels and the PPI drugs had to be discontinued. This would not have been the case if researchers had been more knowledgeable about magnesium supplementation and how to more effectively administer it.

Hypomagnesemia is under-recognized and under-reported, yet clinically serious adverse events are commonly reported symptoms of hypomagnesemia. One of the hidden dangers of hypomagnesemia is that it produces impaired parathyroid hormone secretion, which may lead to hypocalcemia.

Information from epidemiological and other studies supports the fact that a low intake of magnesium increases the risk of developing and/or dying from cardiovascular disease or stroke. Thus increasing the magnesium intake from water is beneficial, especially for populations with an insufficient dietary intake of the mineral, which means everyone.[1],[2] Yet the American government chooses to put highly toxic fluoride in the public water systems instead of magnesium.

The UN’s World Health Organization (WHO) has recommended that drinking water contain 25-50 mg of magnesium per liter to prevent deaths from heart attack and stroke. American bottled water averages < 5 mg of magnesium (Mg) per liter, while bottled water in the rest of the world averages about 20 mg of magnesium per liter.

Paul Mason, famously known as the magnesium librarian, wrote, “The evidence has been overwhelming that Americans are very deficient in Mg, as evidenced by the 23% shortfall from the RDI, yet the FDA and DOJ have covered up keeping silent about the millions of deaths indicated by over 50 epidemiological studies from nine countries. Recent studies clearly confirm that water-borne Mg is far, far better in preventing cardiovascular pathologies than food-borne Mg.” Mason is the owner of a water mine that has the highest levels of magnesium and bicarbonate in the world!

Drs. Burton and Bella Altura say that ideally water should contain 100 mg of magnesium per liter. Normally one has to add pure magnesium chloride to one’s water supply to attain such optimal levels. Personally I just add a few sprays of Ancient Minerals magnesium oil to a little cup of water and chug it down like whisky; it can taste pretty strong but it makes an excellent nutritional supplement. See my essay on Combining Oral and Transdermal Dose Sensitivity and Therapeutic Effect.

People who have had magnesium injections for years to prevent spasms in their arteries and veins have been able to get off of the injections by consuming enough magnesium-rich water. When treating oneself for magnesium deficiency, which occurs easily from drinking magnesium-deficient water and eating a host of processed “white” foods, there is nothing like the transdermal approach to recover one’s cellular magnesium levels.

Dr. Rath said, “Drugs are generally synthetic, non-natural substances that we absorb in our bodies. Our bodies recognize these synthetic drugs as ‘toxic,’ just like any other non-natural substance. Thus, all synthetic drugs have to be ‘detoxified’ by the liver in order to eliminate them from our bodies. This detoxification process requires vitamin C and other cellular nutrients as cofactors. Many of these essential nutrients are used up in biological (enzymatic) reactions during this detoxification process. One of the most common ways for eliminating drugs from our bodies is called ‘hydroxylation.’ The strongest ‘hydroxylating agent’ in our body is vitamin C, which is literally destroyed during this detoxification process. Thus, long-term use of many synthetic prescription drugs leads to chronic vitamin C depletion in the body, a form of early scurvy, and the onset of cardiovascular disease.”[3]

# # # #

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Dr. Mark Sircus AC., OMD, DM (P)

Director International Medical Veritas Association
Doctor of Oriental and Pastoral Medicine

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For questions pertaining to your own personal health issues or for specific dosing of Dr. Sircus's protocol items please seek a consultation or visit our knowledge base to see if your question may have been answered previously.
  • Michellealeta

    Hello Dr. and Claudia,
    I made inquiry July 17 re my mother and I having a consult with Dr. Sircus-(-probably wasn’t clear what I actually needed as I didn’t get a reply from you)l–couldn’t think of correct terminology at the time I wrote. What type of lab work would Dr. need from me for him to diagnose after consult as I’m going to US soon and would like to know what type of tests to request from my family practitioner who is a regular M.D.He usually does blood work so can you let me know specifically what Dr. would need for me to request. For example, my mother has a thyroid condition so that would be requested. I am previous diabetic and would need that test requested. Are there any other tests via my blood work that you would need?
    I realize Dr. doesn’t recommend doctors stateside, but I’d like to know which type of doctor would I see who follows Dr.’s protocol concerning iodine, calcium, magnesium etc–would it be a holistic dr, allopathic, naturalpathic, chiropractic or what? I’m going to Charlotte, NC and looking in phone book don’t see many choices in these areas of expertise! Kind of frustrating– OH WELL!:) Thanks for any info you can provide. Sincerely yours, Michellealeta

    • Claudia – IMVA Staff

      Dear Michaeleata,

      I’m sorry but we don’t keep a list of doctors in the states that follow Dr. Sircus’ protocol but it would be good if you can find a naturopathic doctor. then when you go see one, he can recommend the testing you need for the various problems you present with.

      Dr. Sircus himself does not rely on any formal testing and the only thing he likes to see is what the ph is running. Being in Brazil he cannot prescribe any other testing for you or your mother. so if you got started on his protocol which you can do without scripts, you would be off to a good start. Start with the magnesium chloride oil, the iodine and the baking soda if needed for pH control.

      Oh, one test you should both have is for kidney function due to the cautions on magnesium if kidney function is decreased…any doctor can do those blood tests and they are routinely done as part of a general examination.

    • Claudia – IMVA Staff


      When you made your appointment with Dr. Sircus for consultation, you should have received directions on what to do before the consult actually occurs which includes providing more information that he will need to make recommendations from.

      • Michellealeta

        ok, thanks. I haven’t made appt with Dr. Sircus as yet because I thought I had to get tests from stateside doctors and wanted to check with Dr. Sircus, but as you explained it will be through naturopathic doctor there yet– Dr. Sircus doesn’t rely on formal testing. Very good!
        Re ph –then is it safe to assume that I can get test strips myself and give Dr. Sircus the results and this should be sufficient in addition to kidney function test?
        My mother has history of Bright’s disease (kidney malfunction). I thought it was reversed by vegan diet and plenty of water and fluids for about 3 years now. I have been massaging her with ancient minerals magnesium oil once or twice a week for about a month. Should I stop this till I get kidney function test when we go to states next month? Oh yes and she is having a blood scan test in Belize later this week at herbalogist which will also, hopefully, show condition of her kidneys. Thanks so much for all the good info and advice. Please continue to inform. Sincerely, Michellealeta

        • Claudia – IMVA Staff


          Be cautious with using magnesium when renal problems are present and check out renal function as soon as possible.

          Keep track of daily pH readings so you can show Dr. Sircus.

  • Michellealeta

    Dear Claudia,
    I live in Central America and will be traveling to US soon hoping to find a doctor that would agree to Dr. Sircus protocol–iodine, magnesium, calcium etc. but not sure what type of doctor to search for–holistic, allopathic, naturapathic, or what!! Anyway, I think I would prefer having a session with Dr. Sircus-not the correct name, but you are following my meaning, I’m sure. I would like to know what type of lab work or reports would Dr. Sircus need for me to obtain while I’m in US, if any, to be familiar with my condition? Both me and my mother will probably need a session. Please advise. Thanks much, Michellealeta

  • My mother is also suffering with magnesium deficiency. The detail’s produced regarding the magnesium deficiency is really helped us. We proceeded further through the link provided in the post regarding the magnesium deficiency of my mother.

  • Michellealeta

    Hi there, Claudia,
    I’m so grateful to have been introduced to Dr. Sircus recently and his interesting info regarding iodine and magnesium. I started logul’s solution about a month ago and have tremendous energy. I plan on tweaking things up a bit and include the beneficial minierals such as selenium to help effectiveness of iodine. In the mean time, I use the transdermal l magnesium on my mother as well as thyroid essentials till I can get all the other minerals to help enhance her lugul’s dosage. I took her off lugul’s temporarily and replaced with’ thyroid essentials’ a product with other ingredients in addition to kelp supposedly beneficial for her condition. We will be traveling to a nd in US and will get further lab testing.
    In the mean time, I have recently read about spirulina and its benefits and uses and that it already contains selenium, b12 as well as a host of other vitamins. Wondering if Dr. Sircus would recommend this in place of the other iodines/iodides on the market? Also, wondering if he would recommend acai berry for its magnesium content? From what I understand spirulina and acai berry have natural, consentrated, unprocessed, for the most part, forms of these minerals and seem to be equally as beneficial. Another one that comes to mind is camu camu–if I spelled it correctly– that’s supposed to be highly concentrated natural form of vitamin c. Would you and Dr. Sircus recommend these powder forms of these minerals for effective treatments as well? Please advise. Thanks much and may God continue to bless.

    • Claudia – IMVA Staff


      Dr. Sircus definitely recommends a good quality spirulina, acai, and whole food sources of vitamin C for use in his protocols. He has written essays on all of these which you can find doing a search on his sites.

      Spirulina is a very important algae substance and is good alone or when combined in a product. A fairly high dosage of spirulina is in Rejuvenate which Dr. Sircus recommends highly. One thing people should be very careful of right now is where their iodine and spirulina is sourced from. Due to the radiation problems in Japan, we are not recommneding anyone get any product from that area, including China unless it was packaged prior to the earthquake. I would be leary of kelp and spirulina coming from those regions affected by radiation and not want to purchase from that area.

      Whole food vitamins are always preferred over synthetic vitamins and in the case of vitamin C, ascorbic acid is not nearly as good as whole food vitamin C. So if a good source for this is found, that’s great. I believe Camu-Camu is a good source.

      • Michellealeta

        Hi Claudia,
        thanks for the reply re spirulina and vitamin c etc. I recently contacted the company where I purchased my spirulina and was told it was from an island in S. China Sea–so apparently, by your answer of not purchasing from Japan, which I knew, and China–which I didn’t know…this would not be a good location or area to purchase from. Where would you recommend that I purchase products to be far from radiation exposure? Please advise. And I will further check out Dr. Sircus sites as I have seen his site on rejuvenate anyway. I may consider purchasing that. By the way, I’ll go back and take another look and see from where that particular spirulina is extracted. Thanks so much for all the good reliable info that you and Dr. Sircus provide. May God continue to bless. Sincerely, Michellealeta

        • Claudia – IMVA Staff

          Dear Michellealeta,

          Thanks for your words of appreciation!

          Its sad to say but at this point we are not sure of the best source for spirulina unaffected by radiation. I think the best thing to do would be to call the companies and ask if they are testing for radiation in their products. We have always recommended Cyanotech (Hawaii), La Molina and Earthrise…….these had assured us of testing for heavy metals ….but really don’t know what they are doing now considering the radiation problem.

          One of the best things we can do for ourselves is to make ourselves as resistant as possible to radiation damage.

          We can accomplish this with Dr. Sircus protocol and we keep searching for good, safe, reliable and reasonabbly priced products for people to use.

  • Margie Kronewitter

    Great article, as always. Plenty news re: Reactor #4. Guess we should up our dosage of everything. Zeolite is my favorite. Wondering how much & how often you reccomend clays? Mahalo~~~ Blessings & Aloha

    • Claudia – IMVA Staff

      Hi Margie,

      You might want to write to the experts at LL’s Magnetic Clay Co. They state that Edible Clay is just as effective as zeolites and don’t see advantage in using them together.

      The recommended dosage for Edible Earth (clay) is 1 tsp. per day in water or juice and I believe Dr. Sircus recommends 2 tsp /day if you are in an area with greater radiation exposure.

      Clay can also be used in baths to help take the radiation out.

  • MaryCW

    Hi Mark, thanks for your blogs – we need more medicos like you who are willing to look beyond the mainstream medicine approach of reactive medicine which relies too heavily on pharmaceutical supplies. So it is great to read articles like yours reflecting “thinking outside the box” and that take a preventative approach to disease. I wonder if you could please give us an article that, instead of talking about ONE element/mineral/vitamin at a time, describes which ones are vital and in what balance. I have been taking iodine/iodide 12.5mg per day for nearly three years and my whole body has benefited in ways I would never have dreamt of. I have never had such a sharp contrast in my well being with any other supplement. I do also supplement with magnesium and selenium as well, but of all the supplements I have ever taken I would have to rank iodine at the very top and a bit of distance then to vitamin C, magnesium and selenium after that. With iodine/iodide I have beaten fibromyalgia, fibrocystic breast disease, a magically improved vascular system and too many other benefits too long to list here!!! However, we do need to have an understanding of how these supplements work together and are best absorbed. So ONE article summarizing them and their interdependence would be great. For example B12 is critical but I understand it isn’t easily absorbed. Also for those of us on limited budgets it would be good to have a fall back list of say no more than 4, 5 or even 6 supplements at the outside that are necessary given our deteriorating environmental conditions (toxins such as fluoridated water, mercury, radiation etc). Understanding the way they work together would also make us aware of what can go wrong with our own supplements. Many thanks, Mary

    • Gilgamesh

      I use moringa powder, and aloe vera juice.
      I think some vitamins, and suppements may have fake ingredients in them,
      and it is confusing, what vitamin, and what dosage? What supplements ?
      My wife also use one hipping teaspoon of moringa powder in a big glass of distilled water,
      and she drinks a half a glass of aloe vera juice a day, and one pound of peanuts.
      Maybe not exactly one pound, she just eat peanuts every day.

    • Claudia – IMVA Staff

      Dear MaryCW,

      Dr. Sircus will be publishing the full prtocol with his top recommendations , hopefully this week or next. It will include how to use each item and what interactions to expect. Watch for our announcement of it.

  • David

    Great new information. Keep ’em coming, Doc!