Massacring Cancer with Oxygen and Bicarbonates

It has long been recognized that solid tumors contain poorly vascularized regions characterized by severe hypoxia (oxygen deprivation), acidosis and nutrient starvation.[1] Over the past decade, work from many laboratories has indicated that hypoxic micro-environments contribute to cancer progression by activating adaptive transcriptional programs that promote cell survival, motility and tumor angiogenesis.[2] Oxygen pulls the … Continue reading Massacring Cancer with Oxygen and Bicarbonates