Metal chelation and detoxification of chemical contaminants are complex and serious matters. It is a fact that you can end up in worse health after chelation than when you started if you are not well-informed and do not proceed carefully under the care of a competent health-care practitioner. Human exposure to heavy metals has risen dramatically in the last 50 years so the need for detoxification and chelation has increased exponentially. (The above book cover is from a beautiful edition of my magnesium book in Portuguese.)
Many of the problems with chelation can be reduced when a person is given sufficient magnesium. The beginning of safe chelation and detoxification starts with magnesium. Magnesium is one of the most important minerals for the human body. Before 2009, it was believed that it was a required co-factor for over 325 enzyme systems, but since then, according to works documented by Dr. Andrea Rosenoff, that number has more than doubled to almost 800 enzymes.
Everyone who is magnesium deficient has a compromised system of detoxification and is more vulnerable to neurotoxins that are increasingly present in our foods and environment. Its deficiency has wide ranging effects and may be responsible for more diseases than any other nutrient. It is more important than calcium because without sufficient magnesium calcium becomes toxic.
In mineral therapy we understand that certain minerals are both the cause (when deficient) and cure of many diseases. Minerals help with everyday body processes, reduce risk of certain cancers, strengthen muscles and tissues, and help develop organs as well as keeping them from deteriorating. Minerals are essential for life, health, and happiness. Minerals are needed to maintain the delicate cellular fluid balance, to form bone and blood cells, to provide for electro-chemical nerve activity, and to regulate muscle tone and activity (including organ muscles like the heart, stomach, liver, etc.)
Magnesium (Mg) is the perfect place to start because not only does Mg help with chelation of heavy metals but at the same time it is nurturing and helping with hundreds of functions in the body meaning it will help people avoid exaggerated healing crises.
The same can be said for bicarbonates so that is a principle reason I either recommend magnesium bicarbonate or a product called pH Adjust, which I happen to take everyday (with clay) everyone morning to maintain my body as free from pollution as possible. However, although pH Adjust has some magnesium, it is not enough.
Bicarbonates are the first medicine to reach for when facing either acute or chronic toxicity and thus should always be used when doing chelation and detoxification. It is powerful enough to clear the kidneys of uranium toxicity and powerful enough to both mitigate the toxicity of chemotherapy. All processes in the body are pH sensitive including chelation and detoxification.
When I was writing 13 years ago my groundbreaking book Transdermal Magnesium Therapy, I called Daniel Reid, the author of The Tao of Detox, in Australia. I asked him about magnesium oil (magnesium chloride), a product that was applied directly onto the skin or put in one’s bath. His reply was simple, “It’s the best detoxification agent I know of.” At that time, only Dr. Norman Shealy was talking about how it could be used this way and the forms that were available back then were not pure enough for oral consumption.
Magnesium protects cells from aluminum, mercury, lead, cadmium, beryllium and nickel, which explains, in part, why re-mineralization is so essential for heavy metal detoxification and chelation. Magnesium is needed not only for the production of specific detoxification enzymes but is also important for energy production related to cell detoxification. A magnesium deficiency can affect virtually every system of the body.
Heavy metals like cadmium, lead, and mercury compete with nutritional magnesium, keeping it from availability to protect our cells. The healthy cell wall favors intake of nutrients and elimination of waste products and this is a principle reason magnesium is so important in detoxification and chelation.
In our age of toxicity, where we are all being poisoned by the chemicals in the air we breathe, the water we drink, the foods we eat, the surfaces we touch, and the medicines we take, we need more, not fewer, critical nutritional agents to help us detoxify our bodies and maintain our health.
For purposes of cellular detoxification and tissue purification, the most effective form of magnesium is magnesium chloride (magnesium oil), which has a strong excretory effect on toxins and stagnant energies stuck in the tissues of the body, drawing them out through the pores of the skin. Chloride is required to produce a large quantity of gastric acid each day and is also needed to stimulate starch-digesting enzymes.
That said there are plenty of other forms of magnesium. I personally like Dr. Carolyn Dean’s ionic form of magnesium and one of the best forms is magnesium bicarbonate, but that cannot be used transdermally like magnesium oil can.
Another reason magnesium chloride is a prime choice is that, "Chloride competes with bromide at the renal level and increases the renal clearance of bromide. It has been suggested that patients require iodine therapy to bring post loading urine bromide levels down and that is just one of many reasons would always recommend iodine.
Dr. Boyd Haley indicates that magnesium in its relationship to ATP provides the crucial energy to remove each toxic substance. Magnesium appears to be a competitive inhibitor of lead and cadmium. As such, increased level of magnesium has been shown to eliminate lead and cadmium through the urine and has also been reported to reduce the toxic effects of aluminum.
 Rauws, A.G., Pharmacokinetics of Bromide Ion-An Overview. Fd. Chem. Toxic., 21:379-382, 1983
There are 5 forms that you can take Magnesium: Oral, Transdermal (Topical), Nebulized and in Baths or Foot Baths, which is another form of transdermal. My favorite though is magnesium massages, which I highly recommend because it combines magnesium medicine with therapeutic touch,
Oral: magnesium chloride is well tolerated and gets absorbed quickly and is inexpensive. The problem with oral magnesium is that all magnesium compounds are potentially laxative. Magnesium chloride can also be taken mixed with juice or water and it can be taken in pill form as well. It makes for a quick medicine for constipation when used this way and is a good complement to transdermal application. Only about 30% of any oral preparation of magnesium is absorbed;
Transdermally: It is one of the best ways to use the Magnesium, because it delivers medications straight to the bloodstream. There is nothing more delicious than a magnesium massage using magnesium oil or gel. The biggest benefit of topical/transdermal magnesium chloride administration is that the intestines are not adversely impacted by large doses of oral magnesium. It can be applied topically to the skin for almost instant therapeutic effect on pain, inflammation and a wide range of other physiological functions like increasing ATP production and oxygen-carrying capacity. It will help with the chelation process if you combine oral with transdermal, as you will be able to take large amounts of Magnesium, increasing your detox process, as the oral may cause nausea or diarrhea.
Nebulization: Magnesium can be nebulized directly into the lungs. Nebulization of magnesium is an alternative method of treatment for patients with pulmonary problems or infections, lung cancer or for those undergoing bronchoscopy. Magnesium nebulized directly into the lungs offers all the same positive therapeutic effects that other types of administration methods do. The lungs are like our inner skin so it is a transdermal type of treatment that concentrates the effects in the lung and bronchial tissues. Nebulizing
Bath or Foot Baths:. A most luxurious and relaxing experience. Use several cups to several pounds of magnesium bath flakes in very warm water before bedtime for ultimate relaxation, relief of aches, pains, to promote sleep, replenish magnesium levels and also detox. You will notice at the end of it the water with black small particulates, which are the toxins going out of your body.
Detox effects of chemicals and heavy metals: Depending on the level of toxicity of your body, you may experience what is called a "healing crisis". This reaction occurs when, toxic substances accumulated in the tissues are released into the bloodstream and cause adverse effects, which means your body is undergoing a cleaning. Symptoms can be an increase in muscle aches, joint pains and even rashes. In cases of adverse reactions, it is recommended to initiate magnesium supplementation slowly, and it increases the dose progressively as the effects diminish.
These are the reactions that appear may appear in our body early in any detox program, even with magnesium.
5- lack of patience
6- excessive sleep
7- itching in the body
8- first monthly flow changed (increased, decreased, delayed or advanced)
9- release of gases (improper feeding)
10- temporary diarrhea (excess of Magnesium)
11- heartburn and burning (must take with full stomach)
12- pain in the kidneys (dissolving the stones in the kidneys)
13- increased pressure caused by the calcium that was clogging the arteries
14- THE PAIN IN THE JOINTS are called "healing pains" and migrate from place to place until they heal all joints ... we do not call the detox effect ... but they occur when Magnesium or MSM (organic sulfur) is correcting something in these joints = => this feeling is VERY COMMON, almost everyone has
15- rare cases report a feeling of tiredness at the beginning ...
16 - Appetite of canker sores
17 - Emergence of pee-existing herpes outbreak
18- rare cases of insomnia when they take the night Magnesium were reported, due to the strong power generation (ATP)
19- changed appetite ... too much hunger or no appetite
20- "dizziness" associated with labyrinth healing