Professor Ardenne wrote, “Because more than 80% of all cancer deaths are caused by metastases, development and evaluation of methods for fighting tumor dissemination should be major tasks of present cancer research. Formation of metastases is favoured by both reduced numbers of immune cells in the bloodstream and impaired oxygen transport into tissues. These closely related signs often emerge concomitantly when the organism is endangered by circulating tumor cells released from the original tumor by therapeutic manipulations. From knowledge of these facts the O2-multistep immune-stimulation technique has been developed as a way of diminishing the risk of tumor spread. The process combines temporary elevation of the number of circulating immune cells with continuous improvement of oxygen transport into tissues.”
When the oxygen saturation of blood falls, conditions then become ripe for the creation of cancer. Oxygen is exchanged and removed from the arterial blood as it passes through the capillary system. If arterial blood is deficient in oxygen or if blocked arteries restrict the blood flow, then tissues oxygenated by the latter stages of the capillary system may be so deprived of oxygen as to become cancerous.
People with various degenerative diseases are often found to have low venous oxygen saturation. Once they receive proper treatment, the venous oxygen saturation level rises and their health and vitality improve dramatically.
Arterial oxygen saturation should ideally be very high. “High O2 tensions were lethal to cancer tissue, 95% being very toxic, whereas in general, normal tissue were not harmed by high oxygen tensions. Indeed, some tissues were found to require high O2 tensions”, J. B. Kizer quoted in “O2Xygen Therapies: A New Way of Approaching Disease” by McCabe, page 82.
He discovered a "switch mechanism" of blood microcirculation, which depends on the oxygen state of the body. A high value of pO2 (greater than or equal to 50 mm of Hg) at the venous ends of the capillaries, attainable by the procedures of the Oxygen Multistep Therapy and by powerful physical exercise as well, results in an increase of the blood microcirculation and, consequently, in a permanent elevation of the oxygen influx and uptake, respectively.
Anti-Inflammatory Oxygen Therapy increases the blood microcirculation and consequently we see a permanent elevation of the oxygen influx and uptake.
If the oxygen state gets worse and declines below a certain threshold, e.g. in progressing age or after long-term distress, the cross sections of the capillaries shrink by swelling of the endothelial cells, and the blood microcirculation will be diminished for an extended period. Reversing this degradation is quite a medical feat.
The utilization of the above-mentioned switch mechanism for permanent improvement of the oxygen flux into all the tissues of the organism is of decisive importance for fighting against the common cause of many diseases, disorders and complaints often going along with increasing age due to an insufficient oxygen (energy) supply for general metabolism.
On Professor von Ardenne’s site they say that, “This switching mechanism is interpreted as a re-enlargement of the capillary narrowed by oxygen deficiency (old age, disease, distress). The re-enlargement appears after increased oxygen uptake of the blood and improved oxygen utilization of human tissue over a certain time period.”
Resolved inflammation restores the blood supply to tissue – and allows the tissue to return to normal aerobic metabolism. Professor Ardenne showed that stress triggers persistent inflammation,which locks an escalating percentage of the body, and muscles into anaerobic metabolism – especially with advancing age.
 Fundamentals of combating cancer metastasis by oxygen multistep immunostimulation processes. von Ardenne M.; Med Hypotheses. 1985 May;17(1):47-65; http://www.ncbi.nlm.nih.gov/pubmed/3892251?ordinalpos=26&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum