Did you know that long-term use of a daily low-dose aspirin dramatically cuts the risk of dying from a wide array of cancers? We just heard in the news that a British research team unearthed evidence that a low-dose aspirin (75 milligrams) taken daily for at least five years brings about a 10 to 60 percent drop in fatalities depending on the type of cancer. But is this the only substance that would dramatically cut the risk of dying from cancer? Are there not safer ways that don’t have the side effects that aspirin does?
Researchers from Japan’s National Cancer Center in Tokyo have found that an increased intake of magnesium reduces a man’s risk of colon cancer by over 50 percent. Men with the highest average intakes of magnesium (at least 327 mg/d) were associated with a 52 percent lower risk of colon cancer, compared to men who consumed the lowest average intakes. Published in the Journal of Nutrition,  the research studied 87,117 people with an average age of 57 and followed them for about eight years. Dietary intakes were assessed using a food frequency questionnaire. Average intakes of magnesium for men and women were 284 and 279 milligrams per day.
Researchers from the School of Public Health at the University of Minnesota also concluded that diets rich in magnesium reduced the occurrence of colon cancer.  And a previous study from Sweden  reported that women with the highest magnesium intake had a 40 percent lower risk of developing the cancer than those with the lowest intake of the mineral.
One would not normally think that magnesium deficiency can increase the risk of cancer yet we will find that just as severe dehydration or asphyxiation can cause death, magnesium deficiency can lead directly to cancer. It is known that carcinogenesis induces magnesium distribution disturbances, causing magnesium mobilization through blood cells and magnesium depletion in non-neoplastic tissues. Magnesium deficiency is carcinogenic, and in the case of solid tumors, a high level of supplemented magnesium inhibits carcinogenesis.  Both carcinogenesis and magnesium deficiency increase the plasma membrane permeability and fluidity.
Anghileri et al. , proposed that modifications of cell membranes are principal triggering factors in cell transformation leading to cancer. Using cells from induced cancers, they found that there is much less magnesium binding to membrane phospholipids of cancer cells compared to normal cell membranes. 
It has been suggested that magnesium deficiency may trigger carcinogenesis by increasing membrane permeability.  The membranes of magnesium-deficient cells seem to have a smoother surface than normal and decreased membrane viscosity, analogous to changes in human leukemia cells. , There is drastic change in ionic flux from the outer and inner cell membranes (higher Ca and Na, lower Mg and K levels) both in the impaired membranes of cancer and of magnesium deficiency. And we find that lead (Pb) salts are more leukemogenic when given to magnesium-deficient rats than when they are given to magnesium-adequate rats, suggesting that magnesium is protective. 
The School of Public Health at the Kaohsiung Medical College in Taiwan found that magnesium also exerts a protective effect against gastric cancer, but only for the group with the highest levels. 
According to the National Foundation for Cancer Research, the value of minerals as part of an anticancer diet is frequently overlooked. However, minerals can play a vital role in fighting cancer. Several studies have shown an increased cancer rate in regions with low magnesium levels in soil and drinking water. In Egypt the cancer rate was only about 10 percent of that in Europe and America. In the rural fellah it was practically non-existent. The main difference was an extremely high magnesium intake of 2.5-3g in these cancer-free populations, ten times more than in most western countries. 
Data suggests that the same holds true for selenium; a diet rich in selenium protects against cancer of the stomach, breast, esophagus, lung, prostate, colon, and rectum. According to Dr. Harold Foster, death rates in the U.S. for cancer are lower when blood selenium levels are high. Those who have studied geographical differences have seen that in low-selenium regions, higher death rates occurred from malignant lymphomas and cancers of the tongue, esophagus, stomach, colon, rectum, liver, pancreas, larynx, lung, kidneys, and bladder. In addition, cancer patients with low selenium levels tend to have a wider spread of the disease, more recurrences, and they die sooner. 
In China, where the selenium levels in the soils varies much more dramatically than in the United States and the population is less mobile, an ecological study in 1985 showed dramatic results in linking cancer with selenium deficiencies. Dr. Shu-Yu Yu measured the selenium content of blood stored in blood banks in 30 different regions in China and classified the regions as high selenium, medium selenium, and low selenium. They then compared death rates from cancer to the selenium rates and found there was an exact correlation. In the low selenium classification, three times as many people died from cancer as in the high selenium classification.
The West African country of Senegal is dominated by high concentrations of selenium in the soil and thus in their foods, and as expected, Senegalese males had the world’s lowest rates for cancer of the trachea, bronchus, lung, stomach, and colon, the fourth lowest for prostate cancer, and sixth lowest for esophageal cancer. Senegalese women had the lowest incidence of cancers of the trachea, bronchus, lung, esophagus, stomach, and colon, and second lowest for breast cancer, and fifth lowest for cancer of the uterus.
Selenium helps stop damaged DNA molecules from reproducing, meaning it acts to prevent tumors from developing. “It contributes towards the death of cancerous and pre-cancer cells. Their death appears to occur before they replicate, thus helping stop cancer before it gets started,” says Dr. James Howenstine in A Physician’s Guide to Natural Health Products That Work.
A 1996 study by Dr. Larry Clark of the University of Arizona showed just how effective selenium can be in protecting against cancer. In the study of 1,300 older people, the occurrence of cancer among those who took 200 micrograms of selenium daily for about seven years was reduced by 42 percent compared to those given a placebo. Cancer deaths for those taking the selenium were cut almost in half, according to the study that was published in the Journal of the American Medical Association on December 25, 1996. In addition, the people who had taken selenium had 63 percent fewer prostate cancers, 58 percent fewer colorectal cancers, 46 percent fewer lung cancers and overall 37 percent fewer cancers. Selenium was found to reduce the risk of lung cancer to a greater degree than stopping smoking. 
Much of the same can be said about the cancer prevention and treatment possibilities of iodine and sodium bicarbonate. Few people know that at least one in every five cancers is caused by infection and that is discounting the theory that cancer is a fungus. To alert public opinion to this little-known fact, a massive campaign by the International Union against Cancer (UICC) on the theme of prevention updates us on the viruses and bacteria that can lead to the deadly disease. "Of the 12 million people who are diagnosed with cancer each year, around 20 percent of cases can be attributed to viral and bacterial infections that either directly cause or increase the risk of cancer," says Professor David Hill, UICC president. Iodine can be taken in high dosages forever since the body needs iodine, whereas it does not need aspirin. Iodine is anti-viral and antibacterial as well as a prime substance that can be used against fungus infections with the mighty mallet of baking soda helping tremendously in this regard.
Minerals are and have always been the primary medicinals that we have to both prevent and treat cancer, and it should be obvious that they are safer to use than aspirin, which is actually quite dangerous to use over the long-term. I recommend that magnesium chloride be chosen as the best magnesium salt and that it should be used both transdermally and orally. Pure magnesium oil with extremely low levels of mercury is the obvious choice — one should avoid using products sourced from the Dead Sea and from the Great Salt Lake in Utah since both areas are very high in mercury contamination.
 “High dietary intake of magnesium may decrease risk of colorectal cancer in Japanese men” Volume 140, Pages 779-785 Authors: E. Ma, S. Sasazuki, M. Inoue, M. Iwasaki, N. Sawada, R. Takachi, S. Tsugane, Japan Public Health Center-based Prospective Study Group.
 Mg2+ is critical for all of the energetics of the cells because it is absolutely required that Mg2+ be bound (chelated) by ATP (adenosine triphosphate), the central high energy compound of the body. ATP without Mg2+ bound cannot create the energy normally used by specific enzymes of the body to make protein, DNA, RNA, transport sodium or potassium or calcium in and out of cells, nor to phosphorylate proteins in response to hormone signals, etc. In fact, ATP without enough Mg2+ is non-functional and leads to cell death. Bound Mg2+ holds the triphosphate in the correct stereochemical position so that it can interact with ATP using enzymes and the Mg2+ also polarizes the phosphate backbone so that the ‘backside of the phosphorous’ is more positive and susceptible to attack by nucleophilic agents such as hydroxide ion or other negatively charged compounds. Bottom line, Mg2+ at critical concentrations is essential to life,” says Dr. Boyd Haley who asserts strongly that, “All detoxification mechanisms have as the bases of the energy required to remove a toxicant the need for Mg-ATP to drive the process. There is nothing done in the body that does not use energy and without Mg2+ this energy can neither be made nor used.” Detoxification of carcinogenic chemical poisons is essential for people want to avoid the ravages of cancer. The importance of magnesium in cancer prevention should not be underestimated.
 Magnesium has a central regulatory role in the cell cycle including that of affecting transphorylation and DNA synthesis, has been proposed as the controller of cell growth, rather than calcium. It is postulated that Mg++ controls the timing of spindle and chromosome cycles by changes in intracellular concentration during the cell cycle. Magnesium levels fall as cells enlarge until they reach a level that allows for spindle formation. Mg influx then causes spindle breakdown and cell division.
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