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HOMEMEDICINEGeneral

Magnesium Administration

Published on December 8, 2009

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MAGNESIUM CHLORIDE INJECTION
200mg/mL (20% w/v), 2.951 mOsm/mL, 50mL Multi-Dose Vial.

The only real challenge with magnesium is getting it into your body, because most products are poorly absorbed and cause diarrhea. But once I solved this problem and was able to increase my magnesium intake, my pain quickly eased and my disorder gradually faded.– Dr. Jay S. Cohen

The use of high oral doses of magnesium has typically been precluded because of magnesium’s tendency to provoke diarrhea in many patients when administered orally. For example, in one study a dosage of 250 mg two times daily of magnesium administered orally produced adverse intestinal effects in 45.7% of subjects. For many years oral dosing was without question the administration route of choice for most doctors and healthcare practitioners. Intravenous drug administration requires that the patient be in a hospital or clinic though when the condition being treated is chronic, this is impractical and expensive.

Administration with magnesium at pharmacologic doses is crucial to treating chronic conditions that are arising from common and persistent magnesium deficiencies. However oral dosing at pharmacologic levels has heretofore been ineffective due to the inability of patients to tolerate such a regimen. This problem is now academic since the advent of transdermal dosing, which has arisen in popularity only in the last three years.

There have been several doctors who have been able to optimize oral intake through several daily administrations, totaling approximately 2-12 times the RDA for magnesium (600 mg to 5 gm elemental magnesium). Dr. Jay S. Cohen, a nationally recognized expert on medications and side effects and the author of The Magnesium Solution for High Blood Pressure submitted a patent with this gradually increasing oral protocol. These higher levels are achieved through increasing daily dosage amounts gradually in response to patient tolerance and using a more well-tolerated form of magnesium preferably a magnesium chloride solution. Total magnesium intake is divided over several doses per day and taken with copious amounts of water.

Orally administered magnesium dosage levels can be increased gradually over time from about 250 to 500 mg elemental magnesium/day to between about 600 mg and about 5000 mg/day elemental magnesium, wherein each orally administered daily dosage amount is divided into smaller doses and orally administered several times per day.  The orally administered daily dosage amount is gradually increased over time and in association with patient’s increased tolerance to the increased dosage, and the administered magnesium is in a solid form or a solution; and maintaining a well-tolerated high-level dosage of orally administered magnesium until cell levels rise and signs and symptoms recede. One retired doctor with diabetic neuropathy was able to tolerate up to 20 grams a day in this way and was able to control his neuropathy.

The preferred magnesium treatment uses a magnesium compound in solution, such as intravenous grade MgSO 4 or MgCl in water or dextrose solution. Other magnesium compounds effective in the present invention include magnesium acetate, magnesium carbonate, magnesium citrate, magnesium gluconate, magnesium glycinate, magnesium hydroxide, magnesium maleate, magnesium orolate, maxnesium oxide, magnesium succinate, magnesium taurate and chelated forms of magnesium with proteins or amino acids.

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If you’re ever rushed to the hospital with a heart attack, intravenous magnesium could save your life. In a 1995 study, researchers found that the in-hospital death rate of those receiving IV magnesium was one-fourth that of those who received standard treatment alone. In 2003, a follow-up study of these same patients revealed an enduring effect of magnesium treatment. Nearly twice as many patients in the standard treatment group had died compared to those who received magnesium, and there were considerably more cases of heart failure and impaired heart function in the placebo group.

In addition to increasing survival after heart attack, IV magnesium also smoothes out arrhythmias and improves outcomes in patients undergoing angioplasty with stent placement. It is also beneficial for acute asthma attacks, often working to relax airway spasms when drugs do not. Magnesium supplementation is crucial for diabetics, too, because it improves insulin sensitivity, helps blood sugar control, and reduces risk of retinopathy.

Therapy with magnesium is rapid acting, has a safe toxic-therapeutic ratio and is easy to administer and titrate.[1] Magnesium is economical, widely available and has a long established safety and tolerability profile in myocardial infarction. Magnesium chloride has the advantage of being administered intravenously, intramuscularly, and orally as well as vaporized through a nebulizer, and as a lotion transdermally. In anesthesia and intensive care, the preferred administration route is IV.

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Magnesium ions cross the intact blood-brain barrier efficaciously so that intravenous magnesium significantly raises cerebrospinal fluid and brain extracellular fluid magnesium levels quickly.

In the 90’s cardiovascular biologist Dr. Burton M. Altura of the State University of New York Health Science Center at Brooklyn witnessed a therapeutic benefit of magnesium in acute symptoms, such as headache pain. Altura administered a solution containing 1 gram of magnesium sulfate intravenously to 40 patients who visited a headache clinic in the throes of moderate to severe pain. They treated not only migraine sufferers but also persons with cluster headaches and chronic daily headaches.

Within 15 minutes, 32 of the men and women—80 percent—experienced relief. Though the headache may not have vanished, the pain lessened by at least 50 percent. In 18 of these individuals, the pain relief lasted at least 24 hours. Blood tests before treatment confirmed that all but four in this latter group had ionized magnesium concentrations that were lower than the average in a related group of pain free individuals. “All nine patients with cluster headaches had their acute headache aborted by magnesium therapy.” Migraine sufferers who responded to the treatment experienced a complete alleviation of their current symptoms, including sensitivity to lights and sound. Subsequent studies of additional migraine patients have confirmed a common pattern, Altura says. “Those patients where ionized magnesium in the brain or blood is low will respond to intravenous magnesium very quickly and dramatically.

The following chapter introduces transdermal medicine, an extraordinary method of magnesium application that has not been studied by allopathic medical science. This chapter focuses on western medicine’s experience with intravenous magnesium infusions and injections. Doctors need to learn though, about and use the wide spectrum of administration routes to harness the full medicinal power of magnesium.

Heart palpitations, “flutters” or racing heart, otherwise called arrhythmias, usually clear up quite dramatically on 500 milligrams of magnesium citrate (or aspartate) once or twice daily or faster if given intravenously.– Dr. H. Ray Evers

Magnesium has minimal side effects in usual therapeutic doses and has a large therapeutic index. The timing and doses of magnesium are critical especially in cases of stroke or heart failure. The Fast-Mag (Field Administration of Stroke Therapy – Magnesium (FAST-MAG) trials are being carried out in Los Angeles to show the beneficial effects of early magnesium administration by paramedics when stroke first occurs. Each year in the US, over 750,000 Americans suffer a symptomatic stroke.

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Magnesium chloride is first aid for the heart.

More than 4 out of 5 strokes are due to ischemic infarction.

The FAST-MAG trial was designed to address the crucial factor of delayed time to treatment, which has hindered past human clinical trials of neuroprotective drugs. Animal studies suggest the duration of the therapeutic window is very brief, generally less than 2-3 hours. Most animal studies of neuroprotective agents initiate therapy within 1-60 minutes after ischemia onset. Because magnesium medicine is poorly understood by western medicine it is rarely used early enough or often enough to benefit from its full potential to save lives or reduce suffering among cardiac or stroke patients.

Cardiac arrhythmias and coronary artery vasospasm can be caused by magnesium deficiency and intravenous magnesium reduces the risk of arrhythmia and death immediately after acute myocardial infarction.[2]

A study published in The Lancet reported the effects of a double-blind, randomized, placebo-controlled study in 2,316 patients with suspected myocardial infarction. The dose of magnesium was high (about 8.7 grams given intravenously over a 24 hour period), but the results were remarkable: magnesium reduced cardiovascular mortality by 25 percent. Teo and colleagues, in an analysis of seven clinical studies, concluded that magnesium (in doses of 5-10 grams by intravenous infusion) reduced the odds of death by an astounding 55%. Two forms of Mg are available, namely Mg chloride and sulfate for infusion. Ten millilitres of a 10% Mg chloride (MgCl2) solution provide 1 g of Mg salts (= 118 mg Mg = 9 mEq = 4.5 mmol), and 10 mL of a 10% Mg sulfate (MgSO4) solution provide 1 g of Mg salts (= 98 mg Mg = 8.12 mEq = 4.06 mmol).

Although intravenous magnesium is the drug of choice at the onset of a heart attack, it is not mentioned in the section on arrhythmias in the 1989 “Compendium of Drug Therapy.”– Dr. H. Ray Evers

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Dr. Sarah Myhill has been using I.V. magnesium in her general practice for over 15 years for both acute and chronic problems. She uses it for all patients with acute chest pain (unless the blood pressure is very low), acute heart failure, pulmonary embolus and acute asthma. Myhill says, “It is a potent vasodilator – i.e. it opens up all the blood vessels. Indeed patients can feel their blood vessels dilating as I give them the magnesium – they warm up all over! This has the immediate effect of reducing the work of the heart and opening up the co-lateral circulation of the heart. Most of the patients with acute heart attacks have their pain completely relieved by I.V. magnesium.”

“I then give them morphine as well (standard treatment) to relax them and take the stress out of the situation. (Anyone having a heart attack will naturally be in fear of their lives – the panic and adrenaline this creates puts even more stress on the heart). It is anti-dysrythmic – most patients who die from a heart attack do so because the pace maker is disturbed and the heart goes off into an abnormal beat. Magnesium is highly protective against this. It inhibits blood clotting and so reduces the likelihood of further clogging of the blocked artery.”

Myhill continues, “It protects against “stunning” or reperfusion injury. After an acute heart attack, the muscle dies and becomes the infarcted area. With recovery there may be renewed blood supply to the damaged area. The damaged heart muscle may not be able to cope with the renewed oxygen supply and suffer stunning – an acute loss of its contractile ability. This may explain deaths which occur a few hours or days after the initial infarction. In the many patients where I have injected magnesium prior to admission to the hospital, I have never had a patient die subsequently. Indeed I can relieve pain quickly and send them on greatly reassured that all will be well. This technique was taught to me by Dr. Sam Browne who documented his cases (Journal of Nutritional Medicine 1994, 169-177).”

Magnesium has been used safely by doctors for over 60 years. Magnesium’s powerful vasodilator action immediately became apparent with its action increasing in potency with increased initial blood concentrations. After magnesium infusions there is a significant increase in cardiac output, and the cardiac index is maintained at a higher level than that of control groups during the induction of anesthesia and endotracheal intubation.[3]

The common procedure of invasive cardiac intervention and intravenous magnesium administration before reperfusion should without question become the gold standard in treatment of acute myocardial infarction.[4] Two meta-analyses studied the impact of magnesium treatment on reduction of the death rate and rhythm disorders in the acute phase of myocardial infarction before initiation of reperfusion treatments. Both reports found a 54% reduction of the death rate, and one noted a decreased incidence (49% less) of ventricular fibrillation or tachycardia in the population treated by magnesium.[5] The most important action of MgSO4 in AMI is to open up collateral circulation and relieve ischaemia thus reducing infarct size and mortality rates.[6]

Magnesium is far down the pre-hospital protocol though and is not commonly used except in the case of early-recognized Torsades de Pointes, which is a special form of polymorphic ventricular tachycardia. Lidocaine is usually the first medication given someone suspected of heart attack, and its benefit is most likely limited to ventricular tachycardia caused by cardiac ischemia.[7]

During myocardial infarction, serum magnesium drops. Heart muscle cells have a high concentration of total magnesium (11–17 mmol•L-1 of intracellular water).2, 6 Hypomagnesemia, defined as a plasma concentration below 0.7 mmol•L-1, is considered severe when under 0.5 mmol•L-1. This condition is most often associated with a true depletion of magnesium in the organism, although a magnesium deficit can exist even when serum magnesium is normal because the serum levels are maintained within strict limits even as cellular levels drop. Measurement of the urinary excretion of magneisum and a loading test can help establish a diagnosis,37 though magnesium deficit can be universally assumed in most critically ill patients. Incidences of deficit are found to be much higher in patients sampled in surgical and medical intensive care units. For patients with variant angina, 24-hour magnesium retention after intravenous magnesium loading was 60%, while it was only 36% in control subjects.

In the emergency treatment of tetanus magnesium infused at doses providing serum concentrations of 2 to 4 mmol•L-1 allowed good control of spasms and muscle rigidity. Intubation and ventilation were only required for 43% of patients, and the overall death rate was 12%.[8]

Studies looking at the beneficial effects of magnesium administration to critically ill patients in the ICU with a wide range of diagnoses showed that after infusion of 5 gm of magnesium in D5W over 6 hours:

1. Heart rate came down within an average of 45 min, rhythm improved from irregular to regular and to good volume.
2. Urine output increased from almost oliguria to 30–40 ml/hour. Creatinine reduced or did not rise any further.
3. Pulmonary edema resolved in 24 hours.
4. Lactic acidosis disappeared within 4–5 hours.[9]

A total of 126 patients with proven angina have been treated with IV MgSO4 and 116 have either been completely relieved of pain or markedly improved.[10] Most patients were given six IV injections of MgSO4 with a total dose of between 24 and 48 mmol of Mg. If the patient is quite happy, the dose is often increased to 8 mmol given on a further five occasions either daily or weekly as is found convenient. In AMI, I give 7 mmol MgSO4 with 5000 units of heparin in about 15 seconds after an initial 1 mmol has been given more slowly. Then, MgSO4 (8 mmol) is given daily for 2-3 days, or for longer if chest pain recurs. A further course of three doses of 8 mmol is given after 2-3 weeks. In AMI, the dose is reduced to 1 mmol or less, repeated at 15-min intervals, if the blood pressure has fallen unduly.

In some patients with AMI, IV MgSO4 can produce a fall in blood pressure which, if not excessive, may be more beneficial than harmful. In severe cardiogenic shock, the dosage of Mg has been reduced from 8 mmol to 1 mmol or even 0.20 mmol repeated at 15-min intervals with blood pressure monitoring until 4 mmol have been given.[11] Singh has reported dramatic improvement in severe shock using an IV vasodilator.[12]

The treatment to fully replete magnesium levels becomes even more urgent when pharmaceutical medications are used because most drugs drive down magnesium levels further.[13] Magnesium deficiency is routinely made worse by the very drugs meant to help heart problems. “Few doctors know that diuretics help flush magnesium as well as potassium from the body. The resulting magnesium deficiency hinders potassium use by the cells. “Magnesium deficiency keeps people from replenishing potassium,” says hypertension expert Dr. Chris Mende.

Special Note: Vasodilators and nitric oxide supplements are products that help your blood vessels to dilate (open up). These are generally used to help address medical issues like coronary artery disease (condition of the heart that makes blood vessels narrow) and hypertension. It helps to know the best way to increase nitric oxide levels.

[1] Crippa G, Sverzellati E, Giorgi-Pierfranceschi M, et al. Magnesium and cardiovascular drugs: interactions and therapeutic role. Ann Ital Med Int. 1999 Jan; 14(1):40-5.

[2] Eisenberg MJ, Magnesium deficiency and sudden death (editorial), AM Heart J 1992 Aug; 124(2):544-9

[3] The Effect of Magnesium Sulphate on Hemodynamics and Its Efficacy in Attenuating the Response to Endotracheal Intubation in Patients with Coronary Artery Disease G. D. Puri, MD, PhD*, K. S. Marudhachalam, MD, DA, DNB*, Pramila Chari, MD, FAMS, MAMS, DA?, and R. K. Suri, MS, FAMst Departments of *Anaesthesia and Intensive Care and tcardiothoracic and Vascular Surgery, Postgraduate Institute of Medical Education & Research, Chandigarh, India http://www.anesthesia-analgesia.org/cgi/reprint/87/4/808.pdf

[4] Smetana, R. Wink, K. Magnesium, acute myocardial infarction and reperfusion injury. Medicine and Konrad Wink, University Clinic Internal Medicine IV (Vienna, Austria). Clin Calcium. 2005 Feb;15(2):261-4

[6] The Case for Intravenous Magnesium Treatment of Arterial Disease in General Practice: Review of 34 Years of Experience S. E. BROWNE MB BCH

[8] Attygalle D, Rodrigo N. Magnesium as first line therapy in the management of tetanus: a prospective study of 40 patients. Anaesthesia 2002; 57: 778–817.[Medline]

[9] Magnesium in the intensive care unit; from 21st International Symposium on Intensive Care and Emergency Medicine Brussels, Belgium. 20–23 March 2001; Critical Care 2001, 5(Suppl 1):P207 http://ccforum.com/content/5/S1/P207

[11] Browne SE. Intravenous magnesium sulphate in arterial disease. The Practitioner 1969: 202: 562-4.

[12] Singh SP. Use of vasodilator drug in shock (letter). Br Med J 1966; 2: 765.

[13] Most therapeutic drugs (diuretics, chemotherapeutics, immunosuppressive agents, antibiotics) cause hypomagnesemia due to increased urinary loss. It is concluded that most of the clinical situations studied show hypomagnesemia due to renal loss, with exception of renal disease.

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Director International Medical Veritas Association
Doctor of Oriental and Pastoral Medicine

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comments

For questions pertaining to your own personal health issues or for specific dosing of Dr. Sircus's protocol items please seek a consultation or visit our knowledge base to see if your question may have been answered previously.
  • Tony Black

    Hi Claudia,i;m starting my Lymphoma dog Gandalf on the top 3 protocol as soon as i can get hold of all the ingredients. Can i ask how i would administer the Transdermal Magnesium please? ie.where on his body, (he is short haired)and will it absorb just as well as a human?
    Thanks

  • tom gilman

    If I buy magnesium in the pill form how much should I take on a daily basis

  • Sunnyshine

    I know Dr. Julian Whitaker gives Magnesium IV therapy as part of his protocol for Afib patients. But, I am in Northern California. Do you know anyone that does magnesium IV therapy in Northern California?

    • Sorry we don’t keep a list. Dr. Sircus believes transdermal magnesium applications to be as effective and safer than IV administration unless IV is needed in an emergency. Using transdermal regularly should help quite a bit. Unless you have a magnesium wasting disease which requires IV or IM magnesium administration.
      Claudia French
      IMVA

  • Thanks for sharing your experience with us here John, and thank you also for your advocacy work on this issue. I look forward to hearing about your conversation with Dr. Lesser who has administered magnesium instead of the pharmaceutical poisons given by others.
    Claudia French
    IMVA

    • jham

      My girlfriend spoke with Lesser today and learned that he learned to inject Mg from an osteopath in Hollywood FL named Marshal Fram who apparently died in ’94. I did a google search and found his old address and phone which is disconnected and I don’t yet know if he had a clinic where there might have been other practitioners who could still be with us who might also have learned from him.

      I hope to speak with Dr. Lesser myself in the next few days to see what I can learn. My girlfriend urged him to consider submitting an article to the Journal of Orthomolecular Medicine or at least to the Townsend Letter for Doctors and Patients about this and he seemed excited about doing that. Dr. Lesser must be in his 80s now and he still sees patients. It saddens me to see the old guard dying off in the field of orthomolecular medicine with not enough new blood coming in to fill the shoes of these giants.

      I am going to call Steven Carter, the editor of JOM to get a list of any of the old timers who are still kicking who might yet share some nuggets of truth with us that needs to be saved before they pass, otherwise, too many of them might take valuable information like this to the grave, that that would be a real shame.

      So many lives are at stake. Far too many have been destroyed by psych meds including my cousin Laurie who killed herself when she was 19 and my cousin Ann who died in a state mental hospital, a victim of her improperly treated illness.

      My grandmother attempted suicide several times and was only narrowly saved the last time when she tried to gas herself with carbon monoxide in her car- she’d put a hose on the tailpipe to run into the car.

      She had 3 sisters who marched straight into the ocean to drown. My cousin Don attempted to kill himself by diving off the flight deck of an aircraft carrier and was only narrowly saved, and one of my brothers almost threw himself in front of the wheels of a freight train.

      I could have been any of them. There but for the Grace of God go I. I came very close once to diving off the water tower on the campus of the college I went to before embarking on my odyssey through the psychiatric system which came so close to killing me and it has taken me more than 30 years to recover from what they did to me.

      I am very grateful to Dr. Sircus for his wonderful book Transdermal Magnesium Therapy. Some day I hope I get the chance to visit his Sanctuary in Brazil. I hope to build a similar Sanctuary in the Philippines with my girlfriend in the near future. I don’t want to live in America any more, and for many of the same reasons Mark became an expat. This country is fast turning into George Orwell’s worst nightmare.

      I feel a tremendous level of respect for Mark’s work. He is a tremendous person, there are far too few people in the world like him.

      He reminds me of my friend Sister Theresa Feist, a nun who was a teacher when she got sick with so called “Schizophrenia”. She too recovered via orthomolecular medicine as I did, and she became a Naturopath.

      She wrote a book called “Schizophrenia Cured” and is in the Orthomolecular Hall of Fame: http://orthomolecular.org/hof/2006/tfeist.html

      She and Mark are my two biggest role models and I wish I knew them both better than I do and I’d love to put them in touch with each other. I have had conversations with Mark, but none in recent years.

      What is his phone # in Brazil? I used to have it, but had a hard drive crash that wiped out much data. I can be reached at jham@iahf.com or at 1-360-945-0352 or toll free North America at 1-800-333-2553 H&W

      I hope I can convince Michael Lesser to submit an article about injecting Mg to help psychiatric patients to the Journal of Orthomolecular Medicine because I’d love to cite this as yet unpublished article in the book I’ve been writing since the 80s that I badly want to complete in 2015. This is a story that simply must be told! Far too many lives have been destroyed by thorazine, and the second generation psych meds they have today are even more outrageously genocidal!

      The two most important minerals in the human body are Mg and Sulfur. I sell the best organic sulfur in the world and have a growing number of wholesalers world wide.

      I have gotten people off every useless Rx drug you can name just by helping them reestablish the sulfur cycle in their bodies and by learning a few very basic things about detoxification and by making some basic dietary changes.

      Anyone can learn to become their own doctor and far more people need to. Andrew Saul has the right idea, and I love his website “Doctor Yourself” http://www.doctoryourself.com

      Too many MDs think those letters stand for “Medical Divinity” and we’re supposed to worship them when what they mostly need is some badly needed humility, a healthy dose of common sense, and enough integrity to actually honor the Hippocratic Oath which they all too often urinate on due to greed. Far too many of them have made money their God and it saddens me, so I keep trying to transcend them all even as I do my best to pray for them.

      “Iligitimi Non Carbarundum” Don’t let the bastards grind you down.

  • jham

    Dr. Sircus recommends using magnesium instead of such psychiatric medications as Zyprexa, Risperdal, Geodon, Seroquel, Clozaril, and Abilify- all of which carry black box warnings about causing diabetes. He sites Mg as being very effective in relieving neurological disorders and also in the prevention and treatment of diabetes. Can you tell me if anyone has ever injected Magnesium Chloride into an agitated psychotic patient instead of psychiatric medication, and are there any referenced articles you can direct me to about this? I am trying to learn all I can about this. I didn’t see anything in Dr. Sircus book about injecting agitated, psychotic patients with magnesium- are you aware of any information about this?

    • Claudia French

      Dear
      jham,

      Your question must be considered in the manner in which it is
      posed. When a person presents to a hospital ER or for admission to a
      psychiatric facility dangers to themselves and to others are likely imminent
      and their aggressive and often violent behaviors need to be quelled immediately
      for everyone’s safety. In my past experience as a psychiatric RN, I have never
      known any doctor to utilize magnesium chloride or sulfate in an attempt to calm people in acute crisis. Magnesium even if given IV may not have the
      rapid action needed in these situations.

      We are aware
      of accounts from other doctors who have utilized magnesium and vit B6 together
      to calm the negative behaviors of autistic children (Dr. Bernard Rimland has
      published about this)

      On the
      Magnesium Library website you can also find accounts of how magnesium added to
      drinking water has quelled the violence in prison settings.

      See these
      essays: Magnesium deficiency apparently increases violent crime: http://www.mgwater.com/violence.shtml

      Violence Prevention through
      Magnesium-Rich Water

      Magnesium-deficiency
      causes serotonin-deficiency with possible resultant aberrant behaviour,
      including depression, suicide, or irrational violence.

      http://www.mgwater.com/prevent.shtml

      Letter to California Youth
      Authority – The Magnesium Web Site

      Jun 22, 2007 … Magnesium deficiency may cause violence, suicide, or depression.

      http://www.mgwater.com/cyalettr.shtml

      It generally would not be acceptable for
      any doctor today working under the regulations of the AMA to veer from their re
      ommended practices of using pharmaceutical drugs such as Haldol, Seroquel,
      Thorazine, Risperdal or the anti anxiety drugs such as Xanax, Librium or Ativan
      when trying to calm a severely agitated person. And these do work rapidly, so they have their place in medicine on the short term use.
      I expect Doctors would get into trouble for not following AMA accepted
      procedures and I have never seen magnesium administered except to people coming
      in for alcohol detoxification, where it was accepted protocol to administer
      magnesium sulfate IM in the hopes of boosting rapidly their drastically
      deficient levels.

      I used to recommend oral or transdermal
      magnesium supplementation to people and to doctors treating them, but was met
      with either disbelief that it would have a positive effect, or chastised for
      such a recommendation. Our medical
      profession has not yet come to see the light when it comes to nutrients and especially
      not to magnesium and the benefit it can have on depression and suicidal
      thinking, agitation, aggressive behavbioirs and violence, Instead they are ruled by Big Pharma and
      follow their edicts.

      Accounts
      of these types of successes with daily use (but not IV use) of magnesium to
      bring up levels and keep them up can be found in the Transdermal Magnesium
      Treatment book.

      Claudia French
      IMVA

  • Leila Sadien Adams

    Hello I Am am integrative doctor in South Africa with Cluster headache and find IV mgso4 an amazing abortive and prophylactic! I just need some help in optimising the dose please!
    I am currently on 4G iv every 3rd day but still find I have a headache on the 3rd day or so. Please help me find the max dose I can take daily for the month I would normally experience 2 or more headaches a day.

    Something like 50mg/kg/day maybe? Would that b safe for a month every 6 months?

    Desperately seeking your assistance

    Dr Leila Sadien

    • Hello Leila,

      Dr. Sircus can help you with this problem in private consultation. You can see your options here:
      http://drsircus.com/consultations/

      There are a few other things that Dr. Sircus has in his protocol that would help in this type of situation. I hope we can assist you.
      Claudia French
      IMVA

  • Ian

    Ian

    I have read the book on Transdermal magnesium therapy . I have some questions that are not covered in the book. I see that magnesium oil is much more expensive than buying flakes. Can one buy the flakes and dissolve the flakes in distilled water and get the same effect as the oil. If one was to dissolve one cup of flakes with one cup of water what would be the concentration of this OIL. Would it have to be diluted further before putting it on the skin ?
    From what I have read it seems that the dosage is a personal one depending on many factors so I suppose it would have to be done by trial and error.

    • Ian,

      You will probably not get the same effect when dissolving magnesium flakes in distilled water as you would when using the pure magnesium oil. The flakes go through different processing and and is not recommended to be used this way. But feel free to contact LL’s Magnetic Clay as they are the experts on the use of the magnesium oil. Their contact # is on their website. Or if you purchased oil from somewhere else, you might want to contact them about this mixing. The flakes are best used in baths.
      When using magnesium oil the dose is not specific and each person has differing needs so yes, there will be trial and error involved.
      Claudia French
      IMVA

  • Mally

    If one were to nebulize the magnesium chloride oil a la Dr Myhill, what would be the ideal dosage? I see how to mix the solution (3.5 teas of mag oil to 100 ml of distilled water) and to take 5 mL for 100 mg of elemental mag. But is that ideally once a day or more often? Is there a safe upper limit in theory?

    Thanks!

    • Mally, how often to nebulize magnesium would depend on what you are treating or attempting to accomplish and you should follow you health care provider guidelines. The US government lists the upper tolerable limit for magnesium by age group at:
      http://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/

      The upper limit for men and women over age of 19 is listed at 350 mg.

      This is given for oral supplementation of magnesium and does not hold true for food based magnesium. However many researchers and doctors feel that the levels recommended for safe supplementation is much too low and some will go as far as stating that up to 2000 mg./day is safe. Considering that we are intaking so much calcium in our diets (up to 8-10x the RDA) and that the calcium to magnesium ratios should be only 1:1 or 2:1 the 350 mg. day is very low. It also should be taken into consideration that inhalation puts magnesium into our bloodstream much faster than oral ingestion. So again, it depends on what you are wanting to accomplish. For most people transdermal application on the skin is very effective.
      Here is Dr. Myhill’s suggestions for nebulization of magnesium:

      http://www.drmyhill.co.uk/wiki/Magnesium_by_nebuliser

      She states that some trial and error must be tolerated and that you will know in a few weeks if you are taking in enough or not.
      Claudia French
      IMVA

  • I was reading a study from a XVI century Jesuit priest whom, after years of suffering from constant arthritis and lower back pain and worse, rheumatoid arthritis, and was eventually cured by magnesium chloride powder. Care to pitch in?Thank you!

    • Magnesium chloride is very helpful for arthritis and back pain. Would love to see this study, can you send it to us please? Or give us a link! Thank you!

      • I started my healing at 61 years old . Ten years ago, I was almost paralyzed, felt sharp twinges in lower back – one “parrot beak” incurable by physicians. After five years, my weigh and body turned in excruciating pain and despite all the treatments, the pain only increased. The I decided it was time to see an expertin the USA. NOTHING COULD BE DONE, the good doctor told me. I would have to learn to live with my pains..
        Now it was a bunch arthritis calcified, stiff in advanced degree. Nothing could be done. The
        ten applications of shortwave and stretches of the column did not stop
        the pain to the point where I can no more lay down and sleep.
        I’d seat until almost falling off the chair, so sleepy. Providentially,
        I went to the Jesuit Scientists Meeting in Porto Alegre (Brazil)and Father Suarez
        said to be easy to cure with magnesium chloride, showing me the little
        book of Father Puig, a Spanish Jesuit who discovered the use of
        magnesium chloride: his hand was hard as calcified, but with this salt was moving like a girl. In Santa Catarina,(Brazil), I soon began to take a dose in the morning and one at
        night, but even so I continued sleeping curled up until approx the 20th day; that
        morning I woke up lying in the without ANY pain..The magnesium chloride for human use, must be of type PA. (Pure for Analysis) and its color and white. Pave is normal, but this does not alter its content quality.

        But walking was still painful. After
        30 days, I got up feeling odd: “Am I dreaming?” Nothing hurt me! I gave
        up a walk through town, feeling, however, the weight of 10 years
        before.
        After 40 days I walked the whole day feeling like my body had no weigh at all and three months later my flexibility increased. Ten months have passed and I doubled almost like a snake.

        Other effects:
        The magnesium chloride fixed my bones. Even more: that my pulse was always below 40 – I’ve thought of pacemaker – normalized. The nervous system was notoriously calm and I gained greater clarity, my blood was de-calcified and fluid. There were other effects, the point several people ask me – “What is happening to you?’you look younger!” – “That’s right.” Importance of magnesium chloride:
        Themagnesium chloride produces the mineral balance, and encourage bodies to their functions (catalyst) such as the kidneys to eliminate uric acid in osteoarthritis; descaling until the thin membranes in the joints and
        the calcify sclerosis, preventing strokes; purifying the blood, vitalizes the brain, develops and retains “high youth” to my age. After 40, the body absorbs less and less of magnesium chloride, yielding age and disease.
        Usage: Dissolve 2 tablespoons of magnesium chloride (33g) in 1 liter of filtered water.
        Should be taken according to age:
        age 20 to 55 years (1 cup of coffee – 50ml);
        age 55 to 70 years (1 ½ cup – 75ml);
        70 years to 100 years (2 cup of coffee – 100ml).
        Take 1 dose in the morning and one dose in the evening.
        When cured, you should take magnesium chloride as a preventative, i.e., as age and 1 x a day (evening).

        Magnesium chloride is not medicine but food. And no contraindication. It is compatible with any medication simultaneously. Magnesium chloride tidies the whole body and is suitable for men and women.
        For
        women, it helps prevent osteoporosis. Also helps immensely those with rheumatoid arthritis : Uric acid deposits in the
        joints of the body, particularly in the fingers, which swell up. This results from a failure in kidney function, just for lack of magnesium chloride. Once cured, continue with normal doses, as prevention.Other issues/problems:
        rheumatism, muscle stiffness, impotence, cramps, tremors, frigidity, stiff arteries,
        lack of brain activity, the nervous system:
        one dose in the morning, afternoon dose, a dose at night.
        Feeling better, go for preventive dose.

        Good luck!

        • Thanks Tatiana,

          Great information!! So glad to hear of your success. Magnesium Chloride is like a wonderful miracle and for me at least works better than so many other things! We use magnesium oil which is a pure source of magnesium chloride from the deep sea. Us so versatile, it can be used for baths, foot soaks, topically on the skin, and even taken orally as its that pure. People use it as eye drops, deodorant (its very effective) and for muscle spasms, atrial fibrillation, to prevent diabetes and to lower insulin resistance, to treat cancers, and the list goes on and on. You would probably like Dr. Sircus’ book on Transdermal Magnesium Therapy, backed by good research. Thank you for sharing!!

          • Dear Claudia that was NOT MY experience but from a Jesuit Priest in France who went through all that. As I told you yesterday, I would have to translate the text into English and did it in a hurry. I am perusing Dr. Sircus items and will certainly get it. Thanks so much for all the info too! Yet I have a question: isn’t there “too much use” of magnesium that could eventually interfere with our kidneys? The other issue is, I can’t inject myself for the love of GOD!. I abhor needles..:)

          • Tatiana….even more thanks for the translation!! Sorry I didn’t realize that at first.
            If your kidneys are not working properly you can have some problems with accumulating magnesium because its mainly the kidneys that gets rid of any excess we might take in. this is very rare though, and most people can use magnesium chloride safely…….just need to increase the amounts used slowly. No need for injections with Dr. Sircus protocol for magnesium use……
            Thanks again!!1

          • Claudia, you are very welcome. My kidneys work just fine but I did have many many years ago ,a kidney stone which was expelled naturally.And the magnesium Dr Sircus is advising here is the injectable one…Yet a friend of mine in Australia already got my tablets in powder but I am wondering if I could still rub it or use it as many other ways as you mentioned above? Thank you!

          • Tatiana, where did you get that recommendation for injectable magnesium chloride from? Did you have a consultation with him? Dr. Sircus only recommends injectable magnesium chloride in very severe cases of intractable magnesium wasting disease, which doesn’t sound like you!
            Kidney stones don’t count for renal insufficiency….and in fact magnesium use goes a long way to helping get rid of kidney stones too and really helps with the pain, also!!
            I’m sure it wouldn’t hurt you to use the transdermal methods for magnesium.

          • I will give it a try!Have a great weekend.

  • Anne

    if epsom salt magnesium is excreted more often, is there more of a kidney challenge than with magnesium chloride?

    • Claudia French – IMVA Staff

      Anne,

      Any supplemental source of magnesium*(but not dietary) can pose a problem when kidney function is compromised. We have not seen differences in various types of magnesium, though there may be some that others might want to inform us of.

      The problem is that in kidneys that are not functioning properly, the magnesium gets absorbed back into the body instead of being properly excreted. So then it tends to build up to high levels. This does not occur when kidneys are functioning normally. Excess are excreted readily.

  • Anne

    sounds like epsom salts might be useless, even if magnesium chloride isnt availabe? or, could cause kidney problems even if kidneys were well functioning earlier?
    would magnesuim levels from magnesium sulfate(epsom salts) stay up long enough to cause a reliable improvement in heart function?
    how much longer do you think the magnesium chloride levels stay up after using? do either one last 24 hours?
    if i find out my relative’s kidney function is normal, and if she can get epsom salts, should she use it for foot baths more than daily?

    i personally use the magnesium flakes from ancient minerals, but only do so one to three times per week. i have problems with high glucose. perhaps i should use it more often.

    • Claudia French – IMVA Staff

      No Anne,

      Epsom salts are certainly not useless by any means. It can be used and many people benefit from the sulfur. If you can’t afford the Ancient Minerals you can still benefit from Epsom salts though it may have to be used more frequently and in greater amounts. It is also very runny for massages but good in baths.

  • Anne

    i will try to do so. i hope she is in the normal ranges so she can use magnesium foot baths to improve her heart.
    you say the epsom salts, if needed to use when magnesium flakes arent available, dont last as long. what do you mean?

    • Claudia French – IMVA Staff

      Anne,

      the magnesium sulfate (epsom salts) is excreted from the body faster than the magnesium from magnesium chloride.. The magnesium from the epsom salts work quickly but is also excreted more quickly from the body so the magnesiumm levels in the body do not go up except for a short time.

  • Anne

    in that case, it must be dangerous to use magnesium for heart problems.
    i thought it would be the help she needed, but now i am afraid to suggest it.

    • Claudia French – IMVA Staff

      Dear Anne,
      Why not see that she gets her labwork and check the BUN and creatinine levels for kidney functioning. The normals can be found on many sites on the Internet.

      Magnesium would help heart problems , helps them greatly, you just need to find out about the kidney functioning and even then you can tell better what amount of caution would be needed for her particular situation.

  • Anne

    thank you about the warning concerning kidney function. she has not said anything about kidneys, but perhaps they have not informed her. i will be cautious with any suggestions.
    they did tell her she has arythmia. are heart symptoms often accompanied by kidney problems?

    • Claudia French – IMVA Staff

      Dear Anne,

      Kidney problems can cause heart problems and both often occur together.

  • Anne

    how would epsom salts for foot baths work when ancient minerals are unavailabe?
    i have a relative living in a remote part of europe and cant afford the shipping costs, but a local pharmacy can get a type of epsom salts they say.

    she is being given several pills, among which are diruretics, im sure, told to wear compression stockings and live in a nursing home.
    she fainted once that i know of, had a red splotchy rash on her legs once, and had, and still has, swollen feet and legs. she says the swelling is less now, a month later.
    i want her to soak her feet each day in magnesium. she is thinking its not allowed by her doctor, but i have said it is natural and wont interfere with her medicines.
    green vegs are hard to get in her part of the world, and seeds and nuts are costly too. i guess she eats a lot of fish and bread. anyway, she is 93 and very active mentally and physically till the episodes i mentioned here, plus, she never had swelling before. i guess a magnesuim shortage finally caught up with her.
    would magnesium foot baths help for the symtoms ahe has? i think they told her she has a heart rythm problem too.

    • Claudia French – IMVA Staff

      Dear Anne,

      This information is too vague to make a recommendation . Some of what you are describing as her symptomms lead me to think there might be decreased kidney functioning at her age (swelling in legs and feet, and use of diuretics). Magnesium can build up in people with decreased kidney function, to toxic levels if not used under doctors care and supervision. However it would help heart problems.

      Epsom salts as a substitute for magnesium chloride can be used but the effects don’t last as long . Please be cautious about your recommendations to your relative.

  • Gillian Solomon

    I have always taken slow mag for restless legs, three during the night when needed, but recently had gastric surgery and cannot take my slow mag ! I’ve been rubbing on magnesium oil , and also making up coco with mashed banana , but I need more and wonder how to get it , as I can’t sleep for muscle cramps . Any ideas . Not sure my local NHS doctor will be keen to give magnesium shots . HELP

    • Claudia French – IMVA Staff

      Dear Gillian,

      Make sure you are rubbing enough magnesium oil on yourself….up to 2 oz/day is needed, and do this before bedtime and as soon as the cramping starts. Baths with magnesium flakes may also help you. …..and I hope you are using Ancient Minerals from LL’s Magnetic Clay. http://www.magneticclay.com/

  • thomas

    I am looking into get the magnesium chloride Injection
    I have contacted my local compounding pharmacy and they are
    looking into ordering but yes you have a doctors script.

    I have a Doc willing to try this way of getting magnesium
    into mo body and see if these will calm down some of my persistent
    symptoms of pain and severe muscle spasms I hope this works.

    What is the protocol for injections I have looked at many books and websites seems to me that the dose most talked about is 50ml 200mg magnesium 2 x a day

    • Claudia French – IMVA Staff

      Dear Thomas,

      Magnesium injections help many people but we cannot recommend dosages for IM injection, only your doctor can do this.

      IMVA recommends topical application of magnesium chloride with Ancient Minerals Magnesium Oil as the next best thing to IV magnesium treatment. You might want to consider that.

  • david monroe

    What can i do to get msgnesium CHLORIDE naturaly?

    • Claudia French – IMVA Staff

      Dear David,

      Eat more green leafy vegetables, spend lots of time floating in the dead sea, and order some Ancient Minerals Magnesium Oil and apply it daily to your body.

  • Matthew Kurzon

    How can I obtain magnesium chloride for injection and syringes?

    I live in Englewood, NJ, USA.

    Thank you.

    • Claudia French – IMVA Staff

      Matthew,

      I believe its only available that way through a doctor or by prescription.

  • carol wetherington

    I have a nebulizer and lung problems off and on. I would like to use the Mg in the nebulizer. Could someone tell me if I nebulize @100percent or what dilution? Thanks. carol RN

  • Nichalus

    I thought this page was supposed to give updated instructions on how to use transdermal magnesium baths. Instead it is just a discussion on intrevenous care related to heart attacks. Where is an updated dosing instruction guide?