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Surviving Sepsis & Fungal Infections

Published on November 6, 2012

Credit: Image courtesy of Medical University of Vienna

Science Daily reports, “With infectious diseases, it is often not the pathogen itself, but rather an excessive inflammatory immune response (sepsis) that contributes to the patient’s death, for instance as a result of organ damage. On intensive care units, sepsis is the second-most common cause of death worldwide. In patients with a severely compromised immune system specially, life-threatening candida fungal infections represent a high risk of sepsis.”

“The working group led by Karl Kuchler in the Christian Doppler Laboratory for Infection Biology (Max. F. Perutz Laboratories at the Vienna Biocenter Campus) has now deciphered the molecular causes of life-threatening inflammatory reactions that are triggered by fungal infections: two highly aggressive types of phagocytes in the immune system (neutrophils and inflammatory monocytes), which however also have a high potential for collateral destruction, mediate the inflammatory reaction during an infection with candida. Certain interferons, the messenger substances used by the immune system, which are excreted during fungal infections, stimulate the influx of immune cell types to infected organs and lead to sepsis.”

“We have been able to demonstrate for the first time that the targeted blockade of this immune response with inflammation-inhibiting drugs can significantly reduce candida sepsis and therefore mortality,” says Karl Kuchler, who used an anti-inflammatory substance in the study.

Science Daily said, “Infectious diseases are the world’s number-one cause of death, with pathogenic fungi being responsible for extremely dangerous infections. Worldwide, more than €6 billion are spent each year on anti-fungal medications, and the total costs of the medical treatment of infectious diseases caused by pathogenic fungi are estimated in the order of hundreds of billions of Euros.”

Dr. Kuchler used pioglitazone and witnessed a reduction in the number and activity of neutrophils and inflammatory monocytes in mice. “The targeted blockade of excessive immune responses could therefore provide new therapeutic approaches to increase the chances of recovery from life-threatening fungal sepsis,” says Kuchler.

Inflammation is the activation of the immune system in response to infection, irritation, or injury. Characterized by an influx of white blood cells, redness, heat, swelling, pain, and dysfunction of the organs involved, inflammation has different names when it appears in different parts of the body. Most allergy and asthma sufferers are familiar with rhinitis (inflammation of the nose), sinusitis (inflammation of the sinuses), and asthma (inflammation of the airways), but inflammation is also behind arthritis (inflammation of the joints), dermatitis (inflammation of the skin), and so on.

Learn a system of medicine that is safe, simple and affordable! Discover Dr Sircus Natural Allopathic Medicine »

Magnesium Principle Effect as Anti-inflammatory

It just so happens that magnesium is the principle substance that modulates cellular events involved in inflammation—no pharmaceuticals are needed. Magnesium deficiencies feed the fires of inflammation and pain. Increases in extracellular magnesium concentration cause a decrease in the inflammatory response while reduction in the extracellular magnesium results in inflammation. Inflammation causes endothelial dysfunction and activated endothelium facilitates adhesion and migration of cancer cells.[1] Magnesium literally puts the chill on inflammation especially when used transdermally.

Dr. Andrzej Mazur, et al. has shown in experimentally-induced magnesium deficiency in rats that after only a few days a clinical inflammatory syndrome develops and is characterized by leukocyte (white blood cell) and macrophage activation, release of inflammatory cytokines and excessive production of free radicals. “Magnesium deficiency induces a systemic stress response by activation of neuro endocrinological pathways,” writes Dr. Mazur. “Magnesium deficiency contributes to an exaggerated response to immune stress and oxidative stress is the consequence of the inflammatory response,” he continued.

Fungal Infections

Fungal infections are very common but doctors worldwide seem myopic about diagnosing serious late-stage, life-threatening fungal infections. Over one million people worldwide are misdiagnosed with tuberculosis, for example, when in reality they have an incurable disease with a similar outlook to many cancers, says a recent report published in 2011 in the Bulletin of the WHO. The disease called “chronic pulmonary aspergillosis” (CPA) is a fungal infection, not a bacterial infection. Is this incurable, totally drug-resistant TB infection fungal or bacterial? It looks very much like, or is identical to, TB when doctors look at it on a chest X-ray and it has very similar symptoms initially. Doctors mistake it for TB and prescribe antibiotics as standard practice.

Because the X-ray features and symptoms are so
similar to bacterial tuberculosis, doctors fail to
recognize it, resulting in many unnecessary fatalities.
World Health Organization

There is no hiding the fact that baking soda, the same stuff that can save a person’s life in the emergency room in a heartbeat, is a primary fungal treatment option of the safest most effective kind. When taken orally with water, especially with water containing high magnesium content, and or when used transdermally in medicinal baths, sodium bicarbonate becomes a first-line medicinal for the treatment of fungus infections.

I recently published about fungal infections, and breast cancer has been found to be associated with increased frequency of mold-fermented cheese consumption. Fungi produce toxic metabolites called mycotoxins that can cause cancer. Aflatoxin is a mycotoxin with carcinogenic potency that is found in inferior peanut butter and other nut and dairy products. Researchers in 1993 examined human breast cancer tissue and found significant carcinogenic aflatoxin within the cancer tissue implicating aflatoxin and thus fungus as a cause of breast cancer.

All Pharmaceuticals Are Dangerous

All pharmaceuticals are dangerous (come with serious side effects) and that’s why we are supposed to need doctors. The granddaddy of all anti-inflammatories is aspirin, which can cause more serious problems than it can alleviate. Most pain and anti-inflammatory medications are not safe; even the over-the-counter pain medications hold unforeseen dangers. Despite more than a decade’s worth of research showing that taking too much acetaminophen can ruin the liver, the number of severe, unintentional poisonings from the drug is on the rise, a new study reports. The drug acetaminophen is best known under the brand name Tylenol. Compounds containing Tylenol include Excedrin, Midol Teen Formula, Theraflu, Alka-Seltzer Plus Cold Medicine, and NyQuil Cold and Flu, as well as other over-the-counter drugs and many prescription narcotics, like Vicodin and Percocet.

For safe medicine in emergency, life-threatening situations we have to turn to magnesium chloride. It was many years ago that I came across Dr. Raul Vergini and his work in Italy using magnesium chloride to fight infectious diseases. He said, “Magnesium chloride has a unique healing power on acute viral and bacterial diseases. It cured polio and diphtheria and that was the main subject of my magnesium book. A few grams of magnesium chloride every few hours will clear nearly all acute illnesses in a few hours. I have seen many flu cases healed in 24-48 hours with 3 grams of magnesium chloride taken every 6-8 hours.”

Dr. Vergini wrote, “In 1915, a French surgeon, Prof. Pierre Delbet, M.D., was looking for a solution to cleanse wounds, because he had found out that the traditional antiseptic solutions actually mortified tissues and facilitated the infection instead of preventing it. He tested several mineral solutions and discovered that a magnesium chloride solution was not only harmless for tissues, but it had also a great effect over leucocytic activity (increases leucocytes to fight infection) and phagocytosis; so it was perfect for external wounds treatment. Dr. Delbet performed a lot of in vitro and in vivo experiments with this solution and he became aware that it was good not only for external applications, but it was also a powerful immuno-stimulant if taken by injections or even by mouth. He called this effect ‘cytophilaxis.’ In some in vivo experiments it was able to increase phagocytosis rate up to 300%.”

He continues, “From a practical standpoint, please remember that only magnesium CHLORIDE—and no other magnesium salt—has this ‘cytophylactic’ activity; probably it’s a molecular and not a merely ionic matter. The solution to be used is a 2.5% magnesium chloride hexahydrate (MgCl2-6H2O) solution (i.e. 25 grams / 1 liter of water).”

Dosages are as follows:

  • Adults and children over 5 years old ………………. 125 cc
  • 4-year-old children …………………………………. 100 cc
  • 3-year-old children …………………………………. 80 cc
  • 1-2-year-old children ……………………………….. 60 cc
  • Children 6-12 months old ………………………….. 30 cc
  • Children under 6 months old ………………………. 15 cc

In acute diseases the dose is administered every 6 hours (every 3 hours the first two doses if the case is serious); then space every 8 hours and then 12 hours as improvement goes on. After recovery it’s better to continue on with a dose every 12 hours for several days.

The best option for oral magnesium intake is found in pure magnesium oil, which is approximately 35 percent magnesium chloride. Though not sold for oral use, the purest form of this magnesium salt is of a much higher quality than any industrially-produced magnesium salt, being that it comes from a 250-million-year-old underground source, and oral consumption is perfectly fine, though the taste is a bit strong.

Personally I have diluted it and put it in my eyes and I know some doctors use it for their IV bags. I have my massage therapist use magnesium oil on my body and drink about thirty sprays in water using the magnesium oil organic sulfur product from Ancient Minerals. Liquid minerals, especially when it comes to magnesium, are much better absorbed than their solid counterparts, which depend on ample quantities of hydrochloric acid for their breakdown. I personally use it orally up to my bowel tolerance level, which is increased when the magnesium is taken with or directly after meals.

It is amazing that pure magnesium chloride is overlooked as the perfect medicine for constipation, not only of the intestines but also for constipation of mind and emotion as well. That is why research has shown it as a premier medication for depression, stress and sleeplessness.

[1] Magnesium and inflammation: lessons from animal models] Clin Calcium. 2005 Feb;15(2):245-8. Review. Japanese. PMID: 15692164 [PubMed – indexed for MEDLINE

# # #


Learn Dr Sircus protocol including dosages, methods, side effects and contra-indications. This bundle includes the special edition of Transdermal Magnesium Therapy, Treatment Essentials and Sodium Bicarbonate eBooks.

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Dr. Mark Sircus AC., OMD, DM (P)

Director International Medical Veritas Association
Doctor of Oriental and Pastoral Medicine

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For questions pertaining to your own personal health issues or for specific dosing of Dr. Sircus's protocol items please seek a consultation or visit our knowledge base to see if your question may have been answered previously.
  • Matthew Groves

    Is the 125cc dosage an oral dosage of the 2.5% MgCl? Or were those intravenous?

  • organicwellness

    Interesting. I know magnesium is usually not considered by most doctors as a factor in many health issues that do not seem to have a logical and “clinical” explanation. I am now searching for information on cervicofacial actinomycosis, a rare bacterial infection where little information is available regarding treatment, that has been the use of penicillin for 6-12 months or other antibiotics if the patient is allergic to it. Any information related to treatment in recent times and from a holistic view to complement the use of antibiotics would be highly appreciated.

  • JP


    I have recently become ill and it seems my symptoms
    are very similar to previous ones from years earlier. I have been
    hospitalized twice in my 20’s which turned out to be blood infections
    that I believe came about after the initial flu/cold virus hit. The symptoms
    included shortness of breath, racing heartbeat, very sudden hot/cold
    flashes that were followed by dizziness, nausea and weakness. Heartburn
    is also present. I have had stomach ulcer problems since my late teens
    as well and I am now in my mid 30’s. Maybe this could this be a factor? Naturally is
    the only way that has worked for me thus far, or at least better than
    what the pharmaceutical department has offered.(For ex. cabbage juice works wonders and is much cheaper) As for Magnesium Gel and baking
    Soda.. I have a bottle of Natural Calm Canada’s Magnesium Gel, Any
    thoughts on applying this, as well as baking soda and the dose’s?
    Medicinal ingredients: Each ml contains Magnesium Chloride (sea water)
    [Magnesium 60mg]….235mg.


    • Maurice Guggisberg

      Dear JP,
      Dr. Sircus has an entire protocol of a number of things that may help you. You can read about his protocol and about dosages in the ebook Treatment Essentials:

      Or you can choose a consultation with Dr. Sircus for an in depth recommendation for you. He is available to take patients via his online clinic.

      Please let me know if I can be of further help.
      Best Regards,
      Maurice Guggisberg
      IMVA Support Team

  • Deb

    Hi Dr.

    Very informative article in deed. my baby girl was diagnosed with EA/TEF and she has undergone gastrostromy surgery for g tube. She 1 month old now and since birth she is in NICU. One day doc informed me that she is having fungal infection and within a week they informed me that they have found pathogens like gram positive and next week gram negative bacteria. She has also developed jaundice now. They are saying it polymicrobeal and she won’t survive. Just wanted to know if you have any different look at this. They are treating her with antibiotics and fluconazolie. They said they are using the highest possible antibiotics :-(. But no response from the baby


    • Dear Deb,

      So sorry to hear about this. Dr. Sircus may have some other solutions for you to consider. Please get a consult with him as soon as you can to discuss what else he would advise.

      Claudia French

  • Phyllys

    Thank you for all your information.
    Please, where can I purchase the supplements without additives that have selenium, copper and zinc.
    Thanks again.

  • Pat Connolly

    I have a toenail fungus, is this a fungus that can cause issues when recovering from surgery? This is how I have interpreted this blog.

  • Daniel

    Dear Dr. Sircus,

    This is a precious information for fungal treatment. What is your recommendation regarding dosage of Bicarbonate and Magnesium and in what frequency?

  • kaycee

    Dr Sircus

    This is amazing information! So this antibiotic resistant TB is not TB at all, it is a fungus!
    I have always thought fungus was behind some really confusing and deadly diseases.
    I have some experience with fungus, in a house I once lived in and almost killed me.
    Fungus can grow in the most in accessible places in the human body and it also can and will
    create a hard covering from which to grow inside of. You must break this covering in order
    to kill the fungus and live. Otherwise you will die. One of the most horrible ones is the one
    that literally hangs from places in your head, as in behind your eyes and grows. It is as horrible as it sounds!! Bless you Dr Sircus you have taught me sooo much. I have literally felt like I have taken a PHD course in Medicine with you! It has helped me and my family immensely, most certainly it has reduced my medical bills to almost nothing!

    I need help with ezcema, my daughter suffers from it. If she accidentally touches fur
    as in a cat a dog etc or even fake fur now. Please help

    • Claudia – IMVA Staff

      Dear Kaycee,

      I was just doing some research on exczema and its treatments today and found that cannabis or marijuana in the form of a cream is very effective against this problem.

      A company called Dixie X is now selling a cream that cxan be used an d is derived from hemp. It has no THC which is the psychoacxtive part of marijuana and so it is legal to pruchasein all the US and soon in Europe.

      Please see:

    • Megan

      Hi Kaycee,
      I’m jumping in on this part because I have been dealing with a systemic candida infection for the past year and I’ve been on fluconazole from multiple urgent cares because I don’t have insurance. I can barely swallow and I have a rash covering my entire body as well as heart problems, constant fatigue and brain/ eye fogginess. I’m really scared and don’t know where to turn. I don’t eat sugar or carbs and I was previously on antibiotics this past year for a UTI that wouldn’t go away. I’m currently taking caprylic acid and oil of oregano but my symptoms just keep getting worse :/
      What did you do to overcome your fungus issue? My apartment smells like mildew and has mold in the walls as well.
      I have one more month here and I’m trying to hang on.


  • Marlene S Jones

    this was an eye-opener; I am going to start using AMMC orally, as well as on my skin, and hopefully my carpel tunnel, which is acting up recently, come to think of it as I slacked off on using mineral oil on my skin. During my last inflammatory bout, I used it on my thumb area and shoulders daily and it relieved the pain/inflammation.
    We humans only learn the hard way. So thank you so very much for this excellent reminder. God, but I am tired of my own stupidity!