Semaglutide—the diabetes and weight-loss drug known by brand names like Ozempic and Wegovy—continues to show its potential to treat many conditions. These weight loss drugs promise the moon, the stars, and the sky! The U.S. trade name for Wegovy is Ozempic. The newest drug of Hollywood and Oprah. Study after study (marketing) is encouraging broader populations to take a drug known to cause Thyroid C-cell tumors, acute pancreatitis, acute gall bladder disease, hypoglycemia, acute kidney injury, anaphylaxis, diabetic retinopathy, increased heart rate, and suicide. Common reactions include nausea, diarrhea, vomiting, constipation, abdominal pain, headache, fatigue, dyspepsia, dizziness, distension, eructation, flatulence, gas reflux, and nasopharyngitis.
It is a dangerous and expensive drug quickly attaining superdrug status. We read Eli Lilly‘s weight loss drug Zepbound, showed benefits in patients with a common type of heart failure. Patients who took Zepbound were 38% less likely to be hospitalized or die because of heart complications and less likely to need to increase their heart failure medication compared with those who received a placebo, the study found. Zepbound also significantly improved heart failure symptoms and physical limitations, Eli Lilly said in a press release.
Before falling head over heels for the research presented about these self-injectable medicines, we know that according to the British Medical Journal (BMJ), a considerable amount of published research, especially in biomedical fields, is deemed unreliable. Factors contributing to this include false positive results, inadequate study designs, and biases in reporting. The peer-review process, while intended to ensure quality, is often insufficient to prevent the publication of flawed studies. There is a tendency for journals to favor positive results over negative or null findings. This bias can distort the scientific literature, as critical negative results that could inform future research are underreported. The pressure to publish novel findings can lead researchers to prioritize sensational results over methodological rigor.
Other recent studies have revealed that these dangeerous drugs may help stop opioid addiction and smoking and even help people live longer. A new study published in the journal Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association now also links semaglutide to a decreased risk of Alzheimer’s disease.
In the study, researchers at Case Western Reserve School of Medicine analyzed three years of electronic records of nearly one million Americans with type 2 diabetes. They compared patients prescribed semaglutide—a glucagon-like peptide-1 (GLP-1) receptor agonist—to those prescribed one of seven other anti-diabetic drugs, including metformin, dipeptidyl-peptidase-4 inhibitors (DPP-4i), and other GLP-1RAs (which mimic the effects of GLP-1s). Patients prescribed semaglutide had a 40% to 70% reduced risk of first-time Alzheimer’s diagnosis, compared to other antidiabetic medications.
“The result is what we expected,” Rong Xu, biomedical informatics professor at Case Western Reserve University and lead researcher on the study, tells Fortune. Given other studies that show semaglutide can help reduce inflammation in the body, prevent neuron damage, promote weight loss, control diabetes, and prevent cardiovascular disease—in addition to helping curb the urge to smoke and drink—Xu says the drug is already lowering risk factors for Alzheimer’s.
“If we can target these risk factors…semaglutide can be beneficial in preventing or slowing down Alzheimer’s disease symptoms or development,” Xu says. “Diabetes itself is a risk factor [for Alzheimer’s],” she says. Because of that, Xu and her team wanted to see if people at heightened risk—those who have diabetes—would have better outcomes with semaglutide versus other diabetes medications. Researchers can’t say that semaglutide does lower Alzheimer’s risk, only that there is a link.
Another new study suggests that GLP-1 agonist medications like Ozempic, which are used for diabetes management and weight loss, may help reduce the risk of overdose and alcohol intoxication in people with substance use disorders. “It helps to underline another significant benefit of this class of medication,” Dr. Angela Fitch, the co-founder and chief medical officer of Knownwell, a company that provides weight-inclusive health care, told ABC News.
The extensive study, published in the journal Addiction, analyzed the health records of 1.3 million people from 136 U.S. hospitals for nearly nine years. That included the records of 500,000 people with opioid use and more than 800,000 with alcohol use disorder. Those who took Ozempic or a similar drug had a 40% lower chance of overdosing on opioids and a 50% lower chance of getting drunk compared to those who didn’t take the medication, the study found.
The Addiction study does not prove that GLP-1 medications directly lower the risks of opioid overdose and alcohol intoxication, only that people taking them seemed to be helped. It only included hospitalizations, so it’s unclear if they will work in less severe cases.
Results from a tiny study suggest that a combination of the diabetes drug Ozempic and an innovative new intestinal procedure could help erase the need for insulin in folks with Type 2 diabetes. The new trial hasn’t yet been published in a peer-reviewed journal and included only 14 patients who reported that after six months of the combo therapy, 12 of the 14 participants with Type 2 diabetes no longer needed supplemental insulin. The findings were presented at the United European Gastroenterology annual meeting in Vienna.
Conclusion
Certain drugs are heavily promoted. Some, like Ozempic, make pharmaceutical companies make a lot of money. Recently, we have seen a lot of communication about fenbendazole and Ivermectin from alternative sources, also being heralded as cure-alls. But we hardly see anything about iodine, selenium, magnesium, sulfur, and bicarbonates, all of which cover a lot of healing ground. These substances address the basics of human physiology and, as such, can be turned into powerful medications with no side effects. When we are deficient in any of the basics, it is almost impossible to recover from or prevent chronic diseases, no matter what more popular medicines a person takes.
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