Sulfur – Insulin – Diabetes

Insulin’s functionality is significantly influenced by its
structural integrity, which is maintained by disulfide bonds.

Heavy metals like mercury, uranium, and lead attack sensitive sulfur bonds. The science of mercury toxicity shows us that mercurials are highly attracted to sulfhydryls or thiols. The mercury atom or molecule will tend to bind with any molecule present that has sulfur or a sulfur-hydrogen combination in its structure. A thiol is any organic compound containing a univalent radical called a sulfhydryl, identified by the symbol SH (sulfur-hydrogen).

Heavy metals clog up receptor sites, break and bend sulfur bonds in
important enzymes like insulin, damage the DNA, and in
general muck up everything to do with healthy biological life.

The most common mode of breakdown is the sulfur-sulfur bonds. Organic sulfur is an acid-forming mineral that is part of the chemical structure of the amino acids methionine, cysteine, taurine, and glutathione.

Insulin has three sulfur-containing cross-linkages, and the insulin receptor has a tyrosine kinase-containing sulfur bond, which are the preferred targets for binding by both mercury and lead. Should mercury attach to one of these three sulfur bonds, it will interfere with the insulin molecule’s normal biological function.

Insulin’s functionality is significantly influenced by its structural integrity, which disulfide bonds maintain. The relationship between insulin and sulfur bonds primarily involves the biochemical interactions affecting insulin signaling and function, particularly in diabetes and metabolic health.

Disulfide bonds are primarily responsible for the strength and shape of proteins. Since sulfur bonds are required for proteins to maintain their shape, and these bonds determine the biological activity of the proteins, we can see why sulfur is critical for health and life itself.

Thiol poisons, especially mercury, and its compounds, reacting
with SH groups of proteins lead to the lowered activity of various
enzymes containing sulfhydryl groups. This produces a series of disruptions
in the functional activity of many organs and tissues of the organism’.
Professor I.M. Trakhtenberg

Sulfur is required for the proper structure and biological activity of enzymes. If you don’t have sufficient amounts of sulfur, the enzymes cannot function properly. This can cascade into many health problems since, without biologically active enzymes, your metabolic processes cannot function properly.

Insulin and Sulfur Bonds

1. Insulin Structure: Insulin is a peptide hormone composed of two chains (A and B) linked by disulfide bonds. These bonds are crucial for maintaining the three-dimensional structure of the insulin molecule, which is essential for its biological activity.
2. Disulfide Bonds: Disulfide bonds are covalent links formed between the sulfur atoms of cysteine residues in proteins. In insulin, these bonds stabilize the hormone’s structure, allowing it to effectively bind to insulin receptors on cell surfaces and facilitate glucose uptake.
3. Role in Diabetes: Proper formation and maintenance of disulfide bonds in insulin are vital for its function. Misfolded or improperly linked insulin can lead to reduced effectiveness, which is particularly relevant in diabetes management. Research indicates that oxidative stress can disrupt these bonds, potentially contributing to insulin resistance.

Dr. Budwig fed terminal cancer patients a mixture of cottage cheese skim and flaxseed oil. The Budwig diet and the Gerson Therapy diet are two leading anticancer diets. The badly needed sulfur protein L-methionine is found in cottage cheese. L-methionine is the essential amino acid responsible for breaking down omega-3 fatty acids. Sulfur is essential for the metabolism of carbohydrates. Sulfur is required for proper assimilation of the alpha amino acids methionine and cysteine.

The National Cancer Institute found that individuals who ate the most allium vegetables (red onions, scallions, garlic, chives and leeks) had a nearly 50% lower cancer risk than those who ate the least. That page on the Cancer Institute has disappeared by one can find similar information here. (This is the first of three essays on sulfur, the next will be on sulfur and cancer and the third will be a general overview.)

The National Cancer Institute found that individuals who ate the most allium vegetables (red onions, scallions, garlic, chives and leeks) had a nearly 50% lower cancer risk than those who ate the least. A large-scale epidemiological Iowa Women’s Health Study looked at the garlic consumption in 41,000 middle-aged women. Results showed that women who regularly consumed garlic had 35% lower risk of developing colon cancer. In another study greater intake of allium vegetables (more than 10 g per day vs. less than 2.2 g per day) was associated with an approximately 50% reduction in prostate cancer risk.

The Hun Hordes of Mercury and Diabetes

Mercury is an essential subject because mercury contamination causes disease. If one does not understand the Hun Hordes of Mercury story, one cannot truly understand diabetes. On August 1st of, 2006, the American Chemical Society published research that showed conclusively that Methylmercury Induces Pancreatic Cell Apoptosis and Dysfunction.[i] Mercury is a well-known toxic agent that produces various types of cell and tissue damage. Yet, governmental health agencies diminish this fact, exposing hundreds of millions of people to levels of mercury harmful to pancreatic health.

Diabetes, Chemical, Heavy Metal, and Radioactive Poisoning

Few in the world of medicine see that diabetes results from poisoning. In volume 18 of Clinical Toxicology in 1981,[ii] there was a write-up about suicide attempts using rat poisoning where all four cases showed hyperglycemia and ketosis. The authors concluded that ingestion of rodenticide could cause diabetes mellitus after they noticed that the onset of diabetes mellitus varied within a very short time after swallowing the poison – only 4 to 7 days.

Medical science avoids telling doctors how sensitive the insulin receptor sites are to chemical poisoning. Patients treated with the atypical antipsychotic agents clozapine and olanzapine are showing increased risk for insulin resistance, according to a study published in the January 2005 issue of The Archives of General Psychiatry, one of the JAMA/Archives journal.[iii] The American Diabetes Association warned people to watch for signs they are developing diabetes, obesity, or high cholesterol if they take Abilify, Clozaril, Geodon, Risperdal, Seroquel, and Zyprexa.[iv]

Researchers were baffled by the increased incidence of diabetes in Appalachia. In West Virginia, the only state entirely in Appalachia, 1 in 10 people aged 18 and older were told by a doctor that they had diabetes in 2002. Dr. Robert B. Walker of Marshall, noting that West Virginia’s incidence of diabetes is 41 percent above the national average, said, “No disease stresses rural West Virginia families and health providers more than diabetes.”[v]

Up and down the eastern part of the United States, we find high levels of mercury. No one in mainstream medicine is taking into account the intensifying increase in background mercury contamination of fish, water, air, soil, and foods or calculating the hundreds of trillions of mercury atoms and molecules absorbed directly each day, day after day, year after year through having gram weight quantities placed directly in the mouth as dental amalgam.

Forms of Sulfur

Organic sulfur, MSM, DMSO, and lipid sulfur are the primary sources of sulfur for medical use. The lipid format allows rapid absorption and superior bioavailability. Each one-drop serving of Lipid Sulfur contains 500 mcg of sulfur.

Chelation of Mercury

For a decade and a half, Dr. Boyd Haley, renowned former chairman of Kentucky University’s chemistry department, has warned us about mercury contamination. Haley’s chelator NBMI is astonishing and should be near the top of protocols for diabetes, cancer, and neurological patients (think autism, Alzheimer’s, and Parkinson’s disease) and for anyone who has had mercury fillings in their mouths as well as for those who live downwind of coal plants, town incinerators, and crematoriums. NBMI reaches the blood-brain barrier and pulls heavy metals out of the brain, bones, and other tissues.

Magnesium and Insulin

Low levels of magnesium can, therefore, impede reactions of many enzymes related to
glucose metabolism as well as insulin receptor function through increased
microviscosity of the plasma membrane, thus decreasing insulin sensitivity.

Magnesium is essential for improving insulin resistance and is inversely associated with triglycerides, body mass index, and inflammation markers. Magnesium is necessary for both the action of insulin and the manufacture of insulin.

In a study from Taiwan, the risk of dying
from diabetes was inversely proportional to
the level of magnesium in the drinking water.
Dr. Jerry L. Nadler

[i] Ya Wen Chen, Chun Fa Huang, Keh Sung Tsai, Rong Sen Yang, Cheng Chieh Yen, Ching Yao Yang,# Shoei Yn Lin-Shiau, and Shing Hwa Liu. Chem. Res. Toxicol., 19 (8), 1080 -1085, 2006. Institute of Toxicology, Department of Laboratory Medicine, and Department of Orthopaedics, College of Medicine, National Taiwan University, Taipei, Taiwan, and Departments of Traumatology, Surgery, and Emergency Medicine, National Taiwan University Hospital, Taiwan

[ii] Gallanosa, AG, Spyker DA, Curnow, RT. Clinical Toxicology, Vol 18. No.4, pages 441-449, 20 references, 1981 Diabetes Mellitus Associated with Autonomic and Peripheral Neuropathy After Vacor Rodenticide Poisoning: A review

[iii] Arch Gen Psychiatry. 2005; 62: 19 – 28.

[iv] Journal Diabetes Care. February 2004

[v] http://musom.marshall.edu/frontlinks/marshall-walterreed.htm