When blood is abundant, nourished, and well-connected, we feel alive. Blood does more than run through our veins and oxygenate cells. It ensures we have nourishment and moisture for the entire body. Blood keeps our tendons, skin, and hair healthy, strong, and flexible. It lubricates joints, allowing for smooth movement. Blood nourishes the mind and is considered the material basis for mental activity. Vital blood ensures good sleep and helps us wake feeling rested.
The definition of blood in Chinese Medicine differs from that in Western Medicine. In the eyes of Chinese Medicine, blood is enlivened with energy (Qi), which moves the blood to nourish every aspect of our body, from the skin and muscles to the brain and deep organs. The quality of blood circulating through our systems helps give us vitality, focus, and even rosy cheeks.
Although we primarily address blood issues in this first section, we cannot separate the blood from the health of the vessel walls. Atherosclerosis is a plague, even touching the young, and tissue hypoxia, or low oxygen conditions, is another serious problem that will be addressed below in the treatment section.
Red blood cells (RBCs) exhibit unique deformability, which enables them to change shape reversibly in response to an external force. This allows RBCs to flow in microvessels while transporting oxygen and carbon dioxide.
Red blood cells must demonstrate healthy separation.
Poor blood viscosity, RBC aggregation, and poor rheology, independently or collectively, are linked to cardiovascular diseases. For example, Neumann et al. claim that “Plasma viscosity and erythrocyte aggregation were more predictive of myocardial infarction (heart attack) than age, male gender, fibrinogen concentration, abnormal ECG readings, or coronary score.” Another study confirms that high blood viscosity has been associated with cardiovascular-related diseases such as stroke, heart attacks, and deep vein thrombosis.
The aggregating property of red blood cells was first described by John Hunter in 1786 and was long considered to be of pathophysiologic importance since aggregation is elevated in many disease states; hence, the term “blood sludging” coined by M. H. Knisely to describe the phenomenon.[i]
The aggregating property of red blood cells (RBCs) refers to their tendency to stick together, especially under low-shear stress conditions (i.e., when blood flow is slow or stagnant). This phenomenon is called rouleaux formation, where RBCs stack like coins. While reversible, excessive aggregation is a marker of inflammation and poor blood rheology (flow properties). Normal aggregation helps RBCs flow efficiently in small vessels and navigate the microcirculation. Excessive aggregation increases blood viscosity, impairs tissue oxygenation, and contributes to vascular disease.
RBC aggregation isn’t just a lab curiosity—it’s a window into the terrain of the blood. High aggregation signals inflammation, poor detox, and oxygen delivery failure. If red cells can’t move freely, life and health can’t move freely. Treating the blood’s terrain—restoring flow, reducing stickiness, and supporting membrane integrity—should be a top priority in chronic disease, cancer, and cardiovascular care.
Causes of Increased RBC Aggregation
- High fibrinogen and immunoglobulin levels (inflammatory proteins)
- Systemic inflammation or infection
- Metabolic syndrome, diabetes, cancer
- Oxidative stress and toxin exposure
- Dehydration or high blood sugar
- Low sulfur levels, which reduce red cell flexibility and antioxidant defenses
Consequences of Excessive RBC Aggregation
- Reduced capillary perfusion
- Tissue hypoxia
- Higher risk of thrombosis (clotting)
- Increased cardiovascular risk
- Impaired detoxification and nutrient delivery
Blood Medicine Treatments For Healthy Blood
Until now, to have one’s blood treated, one would have to use all kinds of sophisticated equipment that was expensive and somewhat dangerous. No longer. For a low cost and without toxic side effects, one can safely treat their blood at home, expecting the same broad positive medical effects that doctors have seen when using older equipment that requires surgical procedures.
- Magnesium: Improves RBC membrane stability and circulation
- Sulfur compounds (like MSM, DMSO, glutathione, and NAC): Increase red cell flexibility and reduce oxidative stickiness
- Bicarbonates and CO₂ therapies: Improve microcirculation and reduce aggregation by restoring proper pH
- Hydration: Prevents sludge-like blood behavior
- Exercise and EWOT (exercise with oxygen therapy): Mobilize RBCs, improve flow dynamics, and open microcirculation.
- Cyclodextrins – Hugely more effective than Statin drugs, which no one should be taking, reverse Atherosclerosis.
- Chlorine Dioxide – Broad acting cleaning, oxygenating substance.
- Hydrogen Inhalation – Powerful antioxidant. Reduces oxidative stress and inflammation in blood vessel walls.
- Intranasal Laser Therapy – Directly treating the blood with infrared.
- Iodine – Broadband antiseptic.
Magnesium is Crucial
Abnormal magnesium-deprived red blood cells lack the flexibility to enter tiny capillaries. Numerous studies have examined the mechanism by which red cells maintain their biconcave shape. One critical factor is the level of red cell adenosine triphosphate (ATP). The interaction of calcium, magnesium, and ATP with membrane structural proteins exerts a significant role in controlling the shape of human red blood cells.
Mitochondrial Function: Magnesium is indispensable for mitochondrial ATP production – it activates enzymes in oxidative phosphorylation and is required for ATP synthase function. Without adequate Mg2+, mitochondria generate less ATP and may leak more electrons (contributing to ROS formation).
Magnesium has a fibrinolytic action, prolongs clotting time, delays peak thrombin time, slows down platelet clumping, and appears to reduce fibrinogen levels, all of which may prevent the development or extension of an infarct. In addition, the vasodilator action opens collateral circulation and reduces myocardial damage.
Magnesium enhances the binding of oxygen to haem proteins. The concentration of Mg2+ in red cells is relatively high, but free Mg2+ is much lower in oxygenated red blood cells than in deoxygenated ones. This suggests some kind of magnesium pump where oxygen climbs aboard the red cells, and magnesium jumps off, only to jump right back on the red cells again.
CO2, Hypocapnia, and Viscosity of Blood
CO2 influences the viscosity of blood. Acute hyperventilation and arterial hypocapnia make blood more viscous. This effect is part of the fight-or-flight response (an immediate stress reaction). While this is useful in the short run to prevent blood loss (due to bleeding), increased blood viscosity significantly strains the heart. It can cause other adverse effects, such as the formation of blood clots.
Chlorine Dioxide and RBC Aggregation: A Biophysical Explanation
- Oxidative Modulation of Blood Components
- Reducing inflammatory mediators that promote cell clumping
- Decreasing fibrinogen activity, which can reduce rouleaux formation (stacking of RBCs)
- Lowering microbe and endotoxin loads, which often increase RBC aggregation through immune activation
- Impact on RBC Surface Charge (Zeta Potential)
- Improved dispersion
- Better microcirculation
- Reduced blood viscosity
- Indirect Effects via Endothelial Health
Chlorine dioxide (ClO₂) is a potent oxidizing agent that can modulate blood viscosity and cell membrane properties. While excess oxidation is harmful, low-dose or controlled ClO₂ exposure may help by:
Healthy red blood cells have a negative surface charge (zeta potential) that keeps them from sticking together. ClO₂ may enhance this repulsion by oxidizing proteins or lipids that interfere with that charge, leading to:
Chlorine dioxide may also support the endothelium by reducing microbial burden and oxidative stress in blood vessels, indirectly improving RBC flow dynamics.
Cyclodextrins: The Blood-Cleansing Molecule
Cyclodextrins are naturally derived cyclic oligosaccharides known for their remarkable capacity to bind lipophilic substances, including cholesterol and toxic compounds, making them potentially revolutionary for vascular health and detoxification. They are already used in pharmaceutical formulations to enhance solubility and reduce toxicity; however, their medicinal potential extends far deeper.
- Improving Blood Flow: Cyclodextrins can reduce cholesterol accumulation in the bloodstream and enhance endothelial function. By improving lipid profiles, they support better oxygen and nutrient delivery and reduce the risk of atherosclerosis.
- Detoxification Support: Cyclodextrins can sequester fat-soluble toxins, binding and mobilizing them for elimination. This includes environmental pollutants, synthetic hormone residues, and cellular waste products.
- Synergy with Magnesium: When paired with magnesium, cyclodextrins act like a delivery and amplification system—earning them the nickname Batman and Robin of cardio medicine. Magnesium supports vascular relaxation, cellular energy, and heart rhythm, while cyclodextrins improve the fluid medium in which these functions operate.
- Suppressed Potential: Despite their safety record and potential for cardiovascular and neurological support, cyclodextrins remain underutilized and largely ignored by mainstream medicine, likely because they threaten the profitability of patented cholesterol-lowering and detoxification drugs.
Cyclodextrins have shown remarkable potential in cardiovascular applications, particularly in improving blood flow and reducing atherosclerotic plaque by extracting cholesterol from arterial walls. Research from institutions like the University of Bonn (2016) demonstrated that cyclodextrins can dissolve cholesterol crystals, promote immune clearance of plaques, and possibly reverse early atherosclerosis. Despite this, they remain virtually unknown in mainstream medicine.
Their suppression follows a familiar pattern: natural or inexpensive compounds that challenge pharmaceutical paradigms are either ignored or actively dismissed. Like magnesium, chlorine dioxide, sodium bicarbonate, and hydrogen, cyclodextrins threaten billion-dollar drug markets—especially those for statins and invasive cardiovascular procedures.
The structure of hemoglobin is easily compromised by heavy metals like mercury (as are all sulfur-bearing proteins like insulin, etc). Disulfide bonds stabilize proteins, including those in hemoglobin. Hemoglobin and sulfur are both essential to life, and their interaction has significant implications for health, especially for oxygen transport, detoxification, and redox balance.
Connections Between Hemoglobin and Sulfur
While sulfur isn’t a direct component of the heme group in hemoglobin, sulfur plays several important indirect roles:
- Red Blood Cell Health: Sulfur is essential for maintaining glutathione, which protects red blood cells from oxidative damage.
- Iron–Sulfur Clusters: These are found in enzymes critical for hemoglobin synthesis and mitochondrial respiration.
- Sulfur-Based Compounds and Oxygen Utilization: Hydrogen sulfide (H₂S), once thought to be toxic, is now recognized as a gaseous signaling molecule that regulates blood pressure and mitochondrial function alongside nitric oxide and carbon monoxide.
Hydrogen Gas as a Selective Antioxidant in Blood Vessels
Hydrogen neutralizes toxic free radicals, such as hydroxyl radicals (•OH) and peroxynitrite (ONOO⁻), without disrupting the essential reactive oxygen species (ROS) used in cell signaling. This is critical in the bloodstream, where oxidative stress can damage red blood cells (RBCs), lipids, proteins, and endothelial cells. H₂ helps maintain blood integrity and vascular health by preventing oxidative degradation.
Hydrogen Improves Blood Rheology. Studies show that inhalation of hydrogen gas can reduce blood viscosity and improve flow by decreasing erythrocyte aggregation. This reduces the risk of thrombosis, hypertension, and stroke, while enhancing microcirculation.
Protection Against Ischemia–Reperfusion Injury. During heart attacks or strokes, sudden reoxygenation creates a surge of reactive oxygen species (ROS) in the blood. Hydrogen inhalation or hydrogen-rich saline dramatically reduces tissue damage in these events by stabilizing the redox balance in the blood.
Hydrogen protects the vascular endothelium—the inner lining of blood vessels—by reducing inflammation and oxidative stress. It improves nitric oxide bioavailability, supporting healthy vasodilation and blood pressure regulation.
EWOT – Exercise with Oxygen Therapy is the breathing of pure oxygen while exercising. This allows additional oxygen to be absorbed by your red blood cells, blood plasma, and tissue fluids.
Vascular Brownout occurs when a hypoxic stress event causes inflammation in the vascular endothelium. This shrinks the inside size of the pipes that carry blood into a bottleneck. Each bottleneck inhibits blood flow, thereby choking off oxygen to the downstream tissue. Also, the Formation of metastases is favored by both reduced numbers of immune cells in the bloodstream and impaired oxygen transport into tissues.
Professor von Ardenne talks about EWOT creating a “Switching mechanism that creates a re-enlargement of the capillary narrowed by oxygen deficiency (old age, disease, distress). The re-enlargement appears after increased oxygen uptake of the blood and improved oxygen utilization of human tissue over a certain period.”
Von Ardenne discovered a “switch mechanism” in blood microcirculation, which depends on the body’s oxygen state. A high value of pO2 (greater than or equal to 50 mm of Hg) at the venous ends of the capillaries, attainable by the procedures of the Oxygen Multistep Therapy and by powerful physical exercise as well, results in an increase of the blood microcirculation and, consequently, in a permanent elevation of the oxygen influx and uptake, respectively.
Intranasal Laser Therapy is another example of an effective therapy with virtually no mainstream recognition despite its elegant simplicity and physiological logic. Just as cyclodextrins quietly clean the blood at the molecular level, intranasal laser therapy uses light to awaken and oxygenate it, shifting redox status, improving microcirculation, enhancing nitric oxide, and modulating inflammation.
Iodine – Bloodstream Defender
While most iodine in the body is concentrated in the thyroid, trace amounts of iodine circulate in the blood, where they act like an internal antiseptic. When iodine is sufficient, the blood carries a silent shield—killing pathogens before they take root. Chronic iodine deficiency has been associated with impaired RBC production, low hemoglobin levels, and a reduced oxygen-carrying capacity. Iodine’s role in detoxification indirectly protects red blood cells from damage by halogens (such as fluoride, bromine, and chlorine) and heavy metals, which otherwise bind to hemoglobin and impair oxygen delivery.
Thyroid hormones—T3 and T4—require iodine, and these hormones directly regulate bone marrow function, blood viscosity, and heart rate. Without iodine, thyroid dysfunction develops, often resulting in anemia, sluggish circulation, and a metabolic slowdown. Healthy blood begins with healthy thyroid function, and the thyroid is starved without iodine. Iodine enhances the activity of white blood cells, increasing their ability to respond to infection.
Symptoms of Blood deficiency (Chinese Medicine)
Symptoms of Blood deficiency can vary significantly, and each person manifests health patterns differently.
- Dizziness, faintness: – for example, on or after exertion, or from standing up too fast from a seated or lying position
- anemia
- anorexia
- anxiety
- blood loss
- brittle and dry nail, hair, and skin
- cold limbs
- depression
- dream disturbed or restless sleep
- easily awakened
- easily startled–boo!
- exhaustion
- feeling of weakness in the limbs and muscles
- lack of warmth–both physically and emotionally
- mood swings
- nervousness
- nervous laughter and laughter at inappropriate times
- pale complexion
- pale nails
- palpitations
- sadness
- scanty or absent periods
- sensation of cold
- slow growing hair and nails
- slow healing and recover
- slow mental thought
- weak immune system
- hand tremors
- poor vision
- dry eyes
- Spasms and cramps of tendons and muscles
- Insomnia
- Numbness of limbs
- Muscle weakness, twitching or trembling
- Ringing of Ears
- In women, menses are scanty and light-colored with a long cycle or no periods at all.
- Your complexion is pallor and pale lips
[i] M.H. Knisely, Intravascular erythrocyte aggregation (blood sludge), in: Handbook of Physiology, Section 2: Circulation, Vol. III, Am. Physiol. Soc., Bethesda, MD, 1965, pp. 2249–2292.
comments